Evidence map›Paper›PMID 39421403›Full record

Article... International Conference on Manipulation Automation and Robotics at Small Scales (MARSS). International Conference on Manipulation Automation and Robotics at Small Scales2023

Magnetic Microrobots as a Platform for Cell Clean Up.

Fatma Ceren Kirmizitas, David Rivas, Sudipta Mallick, Scott DePope, Sambeeta Das

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ... International Conference on Manipulation Automation and Robotics at Small Scales (MARSS). International Conference on Manipulation Automation and Robotics at Small Scales, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fatma Ceren KirmizitasDepartment of Mechanical Engineering, University of Delaware, Newark, DE 19716.
David RivasDepartment of Mechanical Engineering, University of Delaware, Newark, DE 19716.
Sudipta MallickDepartment of Mechanical Engineering, University of Delaware, Newark, DE 19716.
Scott DePopeDepartment of Mechanical Engineering, University of Delaware, Newark, DE 19716.
Sambeeta DasDepartment of Mechanical Engineering, University of Delaware, Newark, DE 19716.

Funding

The eye as a window into sickle cell disease morbidityP20GM109021 · NIGMS · NEMOURS CHILDREN'S HOSPITAL, DELAWARE · PI HILDENBRAND, AIMEE K · 2014 to 2025
$20.7M
Controlling Cellular Fate using MicromachinesR35GM147451 · NIGMS · UNIVERSITY OF DELAWARE · PI Sambeeta Das · 2022 to 2026
$2.0M
NIGMS NIH HHS P20 GM109021NIGMS NIH HHS R35 GM147451
6 · The paper itself

Abstract

Mobile magnetic microrobots have been extensively used in a wide range of biomedical applications due to their numerous advantages. Magnetic microrobots in particular have been developed and shown great potential over the past two decades for the manipulation and migration of both single cells and cell aggregates. The efficient clearance of cell aggregates is crucial to prevent uncontrolled cell proliferation, tissue damage, and invasive surgeries, especially for those related to the vascular system. In this work, we showed cellular manipulation and mobility to achieve cellular clean up on Human Liver Cancer (HepG2) cells by using two types of untethered magnetic microrobots that are different in type and size. We performed the cellular clean up in the microchannel, which can demonstrate the closed working environment, and also on a glass slide to present an air-liquid interface. We showed that the microrobots could be able to move a cluster of cells in both conditions which could make them useful for sorting and separation applications. Furthermore, cell viability was assessed by using a trypan blue staining assay on HepG2 cells right after and 24 hours after microrobot actuation.

Indexed as

Cell Clean upMagnetic MicrorobotsSingle-Cell Manipulation

Identifiers

PMID39421403
PMCPMC11484213

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.