Evidence map›Paper›PMID 39421139›Full record

ArticleEuropean heart journal open2024

Short-term impact of cardiovascular screening by traditional risk assessment or coronary artery calcium score on health-related quality of life: the ROBINSCA trial.

Dana Moldovanu, Harry J de Koning, Marleen Vonder, Jan Willem C Gratama, Henk J Adriaansen, Jeanine E Roeters van Lennep, Rozemarijn Vliegenthart, Pim van der Harst, Richard L Braam, Paul R M van Dijkman and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dana MoldovanuDepartment of Public Health, Erasmus MC, University Medical Centre Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-3211-0856
Harry J de KoningDepartment of Public Health, Erasmus MC, University Medical Centre Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-4682-3646
Marleen VonderDepartment of Epidemiology, University Medical Centre Groningen, University of Groningen, Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.ORCID https://orcid.org/0000-0001-6718-1887
Jan Willem C GratamaDepartment of Radiology and Nuclear Medicine, Gelre Hospitals, P.O. Box 9014, 7300 DS Apeldoorn, The Netherlands.ORCID https://orcid.org/0000-0001-7483-4997
Henk J AdriaansenClinical Chemistry and Hematology Laboratory, Gelre Hospitals, P.O. Box 9014, 7300 DS Apeldoorn, The Netherlands.ORCID https://orcid.org/0000-0003-0444-0436
Jeanine E Roeters van LennepDepartment of Internal Medicine, Erasmus MC, University Medical Centre Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-6870-9962
Rozemarijn VliegenthartDepartment of Radiology, University of Groningen, University Medical Centre Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.ORCID https://orcid.org/0000-0002-7262-3376
Pim van der HarstDepartment of Cardiology, University Medical Centre Utrecht, Utrecht University, P.O. Box 85500, 3508 GA Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-2713-686X
Richard L BraamDepartment of Cardiology, Gelre Hospitals, P.O. Box 9014, 7300 DS Apeldoorn, The Netherlands.
Paul R M van DijkmanDepartment of Cardiology, Leiden University Medical Centre, Leiden University, P.O. Box 9600, 2300 RC Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-0255-7860
Matthijs OudkerkInstitute for Diagnostic Accuracy-iDNA, Prof. E. D. Wiersmastraat 5, 9713 GH Groningen, The Netherlands.ORCID https://orcid.org/0000-0003-2800-4110
Carlijn M van der AalstDepartment of Public Health, Erasmus MC, University Medical Centre Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Evidence on the impact of screening for cardiovascular diseases (CVDs) on health-related quality of life (HRQoL) is important for policy decisions about screening implementation and to uncover teachable moments to motivate healthy lifestyle choices. It is unknown whether screening by cardiac computed tomography (CT) scan has a stronger impact on HRQoL than screening by traditional risk prediction models. The study aims to investigate differences in HRQoL across the screening process between participants who were randomized to CVD risk estimation by coronary artery calcium score or Systematic COronary Risk Evaluation. Methods and results: A subset of 2687 ROBINSCA participants filled in questionnaires at (T0) randomization, (T1) invitation, (T2) 1-3 days before screening, (T3) 1-3 days after, and (T4) screening result. Generic HRQoL (SF-12; EQ-5D) and anxiety (STAI-6) were measured. We investigated the differences in changes in HRQoL across the screening process with linear mixed models. We found comparable levels of HRQoL at all screening moments for the two intervention groups. Mental health scores were worse at invitation and randomization than at the later time points, irrespective of screening group (all Conclusion: Computed tomography screening for CVD risk has no detrimental impact on HRQoL and anxiety levels compared to screening by traditional risk assessment. Receiving an invitation to screenning or a result implying increased CVD risk could function as teachable moments for high-risk individuals. Registration: ROBINSCA trial registration number: NTR6471 in Dutch Trial Register (NTR).

Indexed as

Cardiovascular diseasesCardiovascular imagingEarly diagnosisMass screeningPsychological distressQuality of life

Identifiers

PMID39421139
PMCPMC11483572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.