Evidence map›Paper›PMID 39421119›Full record

ArticleCureus2024

Giant Cell Tumor of the Central Skull Base.

Anuj Shah, Jacob Mesenger, Benjamin Schwartz, Gaurav Saigal, Sameer Samtani

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anuj ShahDepartment of Radiology, University of Miami Miller School of Medicine, Miami, USA.
Jacob MesengerDepartment of Radiology, University of Miami Miller School of Medicine, Miami, USA.
Benjamin SchwartzDepartment of Radiology, University of Miami Health System/Jackson Memorial Hospital, Miami, USA.
Gaurav SaigalDepartment of Radiology, University of Miami Health System/Jackson Memorial Hospital, Miami, USA.
Sameer SamtaniDepartment of Radiology, University of Miami Health System/Jackson Memorial Hospital, Miami, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giant cell tumor (GCT) of bone is an uncommon indolent tumor, typically occurring in the meta-epiphysis of long bones in young adults. GCT arising in the clivus is exceedingly rare, and even more uncommon in the pediatric population. We present a case of a 13-year-old patient diagnosed with a large GCT in the clivus. Initial clinical and radiographic findings were suspicious for a GCT, although other more common skull base tumors were also considered in the differential diagnosis. Certain key radiographic features suggested the diagnosis of a GCT, including the low T2 signal within the mass on MRI and the T2 hypointense rim corresponding with a cortical shell present on CT. An endoscopic biopsy confirmed the diagnosis. This report highlights the unique diagnostic challenges and broad differential in this case while underscoring the role of imaging in detection and precise anatomic delineation that helps guide therapeutic decisions and improve patient prognosis.

Indexed as

clivusgiant cell tumormagnetic resonance imagingneurosurgerypediatric oncologyskull base tumor

Identifiers

PMID39421119
PMCPMC11485220

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.