ArticleSmart medicine2024
Photothermal responsive porous hollow microneedles as Chinese medicine versatile delivery system for wound healing.
Article in Smart medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Functionalized bio-patches for intra-abdominal applications.iScience · 2026Review
- Machine Learning-Guided Near-Infrared Laser Processing for Precise Geometry Control in Microneedles with Downstream microLED-Triggered Photothermal Functionality.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Polymeric microneedles for closed-loop drug delivery: from biosensing to therapy.RSC advances · 2026Review
- Freeze-Derived Microporous Biomaterials for Tissue Engineering Applications.Smart medicine · 2026Review
- Breaking the vicious cycle of diabetic wounds with an exosome-engineered dual-responsive microneedle patch.Materials today. Bio · 2026Article
- Review
- Microfluidic 3D-printed MSC-laden bioactive hydrogel for intrauterine adhesion prevention and endometrial regeneration.Materials today. Bio · 2026Article
- Interdisciplinarity traditional Chinese medicine microneedles in skin disease treatment: Recent advances and challenges.Bioactive materials · 2026Review
- Engineered Inner Ear Drug Delivery Systems for Hearing Loss Treatment.Research (Washington, D.C.) · 2026Review
- Acellular fishbone scaffolds loaded with bone marrow mesenchymal stem cell-derived exosomes for bone defect repairing.Journal of nanobiotechnology · 2025Article
- Polydopamine-Integrated Porcine Small Intestine Decellularized Extracellular Matrix Hydrogel Microparticles for Wound Healing.Smart medicine · 2025Article
- A matrix metalloproteinase-responsive hydrogel with spatially orchestrated delivery of stem cells and raleukin for enhanced bone regeneration.Materials today. Bio · 2025Article
- Janus Hydrogel Microparticles with Tea Polyphenol/Melanin Nanoparticles Integration from Microfluidics for Wound Healing.Small science · 2025Article
- MSC-encapsulated porous microparticle eye drops for autoimmune dry eye disease treatment in NOD mice.Science advances · 2025Article
- Pollen Integrated Hydrogel Patches With Hierarchical Structures and Spatio-Temporal Actives Release for Wound Healing.Smart medicine · 2025Article
- Resveratrol-loaded engineered microcapsules with dual antimicrobial and ROS-scavenging for programmed wound healing.Materials today. Bio · 2025Article
- Tβ4-Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Biomaterial-based drug delivery systems in the treatment of inner ear disorders.Journal of nanobiotechnology · 2025Review
- Multifunctional Silk and Gelatin Composed Microneedle Patches for Enhanced Wound Healing.Smart medicine · 2025Article
- Hierarchical Micro/Nano-Structured Biomaterials for Wound Healing.Research (Washington, D.C.) · 2025Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chinese medicine is identified as a candidate for wound healing. Attempts in this field tend to develop efficient dosage forms for delivering Chinese medicine with low side effects. In this paper, we proposed novel photothermal responsive porous hollow microneedles (PRPH-MNs) as a versatile Chinese medicine delivery system for efficient antibacterial wound treatment. The PRPH-MNs are composed of porous resin shells with good mechanical property, hydrogel cores, and a photothermal graphene oxide hybrid substrate. The hollow structure provides sufficient space for loading the drug dispersed hydrogel, while the porous resin shells could not only block the direct contact between drugs and wound sites but also provide channels for facilitating the drug release from the core. In addition, benefiting from the photothermal effect of their substrate, the PRPH-MNs could be heated under near-infrared (NIR) irradiation for controllable promotion of drug release. Based on these features, we have proved that the antibacterial Chinese medicine Rhein loaded PRPH-MNs were effective in promoting wound healing due to their good antibacterial property and on-demand drug release. Thus, we believe that the proposed PRPH-MNs are valuable for delivery of different drugs for clinical applications.
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