Evidence map›Paper›PMID 39420874›Full record

ArticleDEN open2025

Propofol-alone sedative efficacy in observational biliopancreatic endoscopic ultrasound.

Hisaki Kato, Yuki Kawasaki, Kazuya Sumi, Yuki Shibata, Norihiro Nomura, Jun Ushio, Junichi Eguchi, Takayoshi Ito, Haruhiro Inoue

Abstract read
In one paragraph

Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hisaki KatoDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.ORCID https://orcid.org/0009-0002-9724-9824
Yuki KawasakiDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Kazuya SumiDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Yuki ShibataDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Norihiro NomuraDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Jun UshioDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Junichi EguchiDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Takayoshi ItoDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.
Haruhiro InoueDepartment of Digestive Diseases Center Showa University Koto Toyosu Hospital Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Appropriate sedative and analgesic selection is essential to reduce patient discomfort and body movement to safely conduct endoscopic ultrasonography (EUS). However, few cases have examined sedation with propofol in EUS, and few studies the need for combined analgesia. In this study, we retrospectively evaluated the usefulness and safety of propofol without analgesics for sedation in biliopancreatic observational EUS. Methods: This single-center retrospective study included 516 observational biliopancreatic EUS procedures using propofol alone performed between April 2021 and March 2023. The primary and secondary endpoints were the observational biliopancreatic EUS results obtained with propofol alone and adverse event occurrence, respectively. Results: The median examination time and total propofol dose were 22 (range: 10-67) min and 186.5 (range: 50-501) mg, respectively. The median starting Richmond Agitation-Sedation Scale and Visual Analog Scale scores were -5 (range: -5-1) and 0 (range: 0-10), respectively. The median recovery time was 22 (range: 5-80) min. Adverse events occurred in 60 (11.6%) patients. Trainee-performed examination (odds ratio [OR] 3.52, 95% confidence interval [CI]: 1.63-7.60, Conclusions: During observational biliopancreatic EUS, propofol is useful as a single sedative and offers high patient satisfaction and relative safety.

Indexed as

analgesicsendoscopic ultrasonographypropofolsedativesedative efficacy

Identifiers

PMID39420874
PMCPMC11483557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.