Evidence map›Paper›PMID 39420855›Full record

ReviewTechnology in cancer research & treatment

The Biological Behavior and Clinical Application Prospects of Deoxythymidine Kinase Gene in Tumors.

Jiayu Zheng, Qiaoqi Wang, Lingxin Yan, Qingyun Pan, Xiangxu Chen, Quanfang Chen

Abstract readReview
In one paragraph

Review in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiayu ZhengDepartment of Respiratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.ORCID 0009-0000-5090-8031
Qiaoqi WangDepartment of Emergency, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Lingxin YanDepartment of Respiratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Qingyun PanDepartment of Respiratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Xiangxu ChenDepartment of Respiratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Quanfang ChenDepartment of Respiratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant tumors have become a significant risk factor for human mortality. Although there have been notable advancements in the treatment of tumors, patient prognosis remains poor. In recent years, gene diagnosis and gene therapy have brought great benefits to patients. Deoxythymidine kinase (DTYMK) is a highly promising biomarker, has been studied by many scholars, and plays a crucial role in the occurrence and development of various types of cancer. The abnormal expression of DTYMK is involved in tumor occurrence and development, and may also serve as a biomarker for tumor diagnosis, treatment, and prognosis. Several experimental studies have shown that DTYMK can impact tumor progression by regulating mechanisms such as cell cycle, tumor microenvironment, immune infiltration, and signaling pathways. Therefore, this article focuses on clarifying the mechanism of DTYMK in tumors and exploring its clinical application value to help patients prolong their survival cycle and improve their quality of life.

Indexed as

Biomarkers, TumorNeoplasmsTumor MicroenvironmentAnimalsGene Expression Regulation, NeoplasticHumansPrognosisSignal TransductionThymidine KinaseBiomarkers, TumorThymidine Kinaseapplication valuedeoxythymidine kinase (DTYMK)malignant tumorsmechanism of actionresearch progress

Identifiers

PMID39420855
PMCPMC11497513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.