Evidence map›Paper›PMID 39420515›Full record

SynthesisJournal of clinical and experimental neuropsychology2024

Cognitive reserve in individuals with frontotemporal dementia: a systematic review.

Lauren A Grebe, Jet M J Vonk, Elizabeth E Galletta, Mira Goral

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of clinical and experimental neuropsychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren A GrebeCommunication Sciences and Disorders, St. John's University, Queens, NY, USA.
Jet M J VonkMemory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA, USA.
Elizabeth E GallettaDepartment of Rehabilitation Medicine, NYU Grossman School of Medicine, New York, NY, USA.
Mira GoralSpeech-Language-Hearing sciences, The Graduate Center, The City University of New York, New York, NY, USA.

Funding

Preclinical markers of Alzheimer's disease using psycholinguistic semantic measuresR00AG066934 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VONK, JET M.J. · 2022 to 2024
$1.2M
Preclinical markers of Alzheimer's disease using psycholinguistic semantic measuresK99AG066934 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI VONK, JET M.J. · 2020 to 2021
$262k
NIA NIH HHS K99 AG066934NIA NIH HHS R00 AG066934
6 · The paper itself

Abstract

As the literature related to cognitive reserve (CR) in individuals with frontotemporal dementia (FTD) is only emerging, a clear consensus on the relationship among CR proxies, brain status, and clinical performance has not been reached. The primary aim of this systematic review was to examine the relationship among sociobehavioral proxies of CR, brain status, and clinical performance in individuals with various types of FTD. Additionally, characteristics of patient population, sociobehavioral proxies, disease severity tools, and brain status measures used were identified. The systematic review was conducted using comprehensive search terms in Medline, PsychINFO, PubMed, and Web of Science. Eligibility criteria were for studies to include at least one CR and one brain status measure for individuals with FTD, be published in a peer-reviewed journal, and be published in English. The Newcastle-Ottawa Quality Assessment Scale was used to assess study quality and bias risk. A total of 237 titles and abstracts were screened, with 13 studies meeting inclusion criteria. Together, these studies report 1,423 participants with FTD. Based on the included studies, partial support was demonstrated for CR in individuals with FTD when education, occupation, and leisure were utilized as CR proxies. The variability in results among studies could be related to the different tools used to measure CR, brain status, and disease severity. This review provides recommendations for future studies: incorporating longitudinal designs, in depth neuropsychological testing, consistent disease duration measure, and transparant statistical output reporting.

Indexed as

Cognitive ReserveFrontotemporal DementiaHumansbrain status measuresCognitive reservefrontotemporal dementiaprimary progressive aphasiasociobehavioral proxies

Identifiers

PMID39420515
PMCPMC11617274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.