Evidence map›Paper›PMID 39420352›Full record

ArticleChild and adolescent psychiatry and mental health2024

Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders.

Erin E Reilly, Sasha Gorrell, Alan Duffy, Dan V Blalock, Philip Mehler, Harry Brandt, Susan McClanahan, Kianna Zucker, Naomi Lynch, Simar Singh and 3 more

Abstract read
In one paragraph

Article in Child and adolescent psychiatry and mental health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Higher and Lower Endorsement of Eating Disorder Symptoms Among Adolescents and Their Caregivers.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Erin E ReillyDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA. Erin.Reilly3@ucsf.edu.
Sasha GorrellDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Alan DuffyEating Recovery Center/Pathlight Mood & Anxiety Center, Denver, CO, USA.
Dan V BlalockCenter of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, NC, USA.
Philip MehlerEating Recovery Center/Pathlight Mood & Anxiety Center, Denver, CO, USA.
Harry BrandtEating Recovery Center/Pathlight Mood & Anxiety Center, Denver, CO, USA.
Susan McClanahanEating Recovery Center/Pathlight Mood & Anxiety Center, Denver, CO, USA.
Kianna ZuckerDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Naomi LynchDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Simar SinghDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Catherine R DruryDepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Daniel Le Grange *Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA.
Renee D Rienecke *Eating Recovery Center/Pathlight Mood & Anxiety Center, Denver, CO, USA.

Funding

CLINICAL SERVICES RESEARCH TRAINING PROGRAMT32MH018261 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kaja Zabrina LeWinn, Rachel L. Loewy · 1985 to 2026
$7.0M
UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Using Computational Modeling to Test Reinforcement Learning as a Predictor of Response in Family-Based Treatment for Adolescent Anorexia NervosaK23MH131871 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Erin E. Reilly · 2022 to 2026
$982k
Neural Correlates of Reinforcement Learning Specific to Hyperactivityin Adolescent Anorexia NervosaK23MH126201 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORRELL, SASHA CATHERINE · 2021 to 2025
$848k
Implementing Family-Based Treatment for Adolescent Anorexia Nervosa for Providers in Private Practice: A Feasibility StudyR34MH123596 · NIMH · STANFORD UNIVERSITY · PI LE GRANGE, DANIEL, LOCK, JAMES D · 2020 to 2022
$731k
Telehealth Treatment of Veterans with Alcohol Misuse at Risk for Cardiovascular DiseaseIK2HX003085 · VA · DURHAM VA MEDICAL CENTER · PI BLALOCK, DANIEL V · 2021 to 2025
–
HSRD VA IK2 HX003085National Institutes of Mental Health K23MH126201National Institutes of Mental Health K23MH131871National Institutes of Mental Health R34MH123596National Institutes of Mental Health T32MH018261NIMH NIH HHS K23 MH126201NIMH NIH HHS K23 MH131871NIMH NIH HHS R34 MH123596NIMH NIH HHS T32 MH018261NINDS NIH HHS R25 NS117367The United States Department of Veterans Affairs Health Services Research and Development (HSR&D) Service IK2HX003085
6 · The paper itself

Abstract

backgroundDespite widespread use of higher levels of care in treating eating disorders in adolescents, research supporting the use of these treatments remains limited by small sample sizes and a predominant focus on anorexia nervosa. Further, existing data regarding predictors of outcome have yielded mixed findings. In the current study, we evaluated treatment outcomes and predictors of outcome among a large sample of adolescents with eating disorders presenting to inpatient, residential, partial hospitalization programs, and intensive outpatient programs across the United States.

methodsAdolescents (N = 1,971) completed self-report measures of eating disorder symptoms, depression, and anxiety at treatment admission, stepdown, and discharge. Using linear mixed effect models, we evaluated changes in symptoms over treatment separately among youth admitted to inpatient/residential treatment and those admitted to partial hospitalization/intensive outpatient programs, and used established metrics to gauge frequency of reliable (i.e., statistically reliable) and clinically significant change.

resultsResults suggested decreases in eating disorder symptoms, depression, and anxiety from intake to discharge. Around 50% of the sample reported reliable decreases in eating disorder symptoms at stepdown and discharge, with 30% of the sample reporting reliable reductions in depression and anxiety. Psychiatric comorbidity, primary diagnosis, age, and eating disorder symptoms at admission consistently predicted treatment-related change, although patterns in findings varied across symptoms.

conclusionsData from our sample are consistent with past work suggesting that adolescents enrolled in higher levels of care report clinical benefit; however, these effects are heterogenous, and a significant portion of individuals may not report reliable change in symptoms. Ultimately, ongoing work is required to better understand how and for whom higher levels of care may achieve their benefit and to identify the optimal approach for improving outcomes for adolescents with eating disorders.

Indexed as

AdolescentsEating disordersHigher levels of careOutcomesTreatment

Identifiers

PMID39420352
PMCPMC11488273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.