Evidence map›Paper›PMID 39420080›Full record

ArticleScientific reports2024

Chronic thyrotoxic myopathy development is associated with thyroid hormone sensitivity index, predicted by lower-limb fatigue and the squat-up test.

Shi-En Fu, Xing-Huan Liang, Li-Li Huang, Jing Xian, Xi-Zhen Wu, Jie Pan, Xue-Lan Chen, Ya-Qi Kuang, Chun-Jiao Wu, Qiao-Li Li and 9 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  2. Chronic thyrotoxic myopathy in an 81-year-old man with Graves disease.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  3. [Frontiers in medicine · 2026
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Shi-En Fu *Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Xing-Huan Liang *Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Li-Li Huang *Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Jing Xian *Department of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Xi-Zhen WuDepartment of Laboratory, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Jie PanDepartment of Neurology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Xue-Lan ChenDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Ya-Qi KuangDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Chun-Jiao WuDepartment of Laboratory, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Qiao-Li LiDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Xiao-Fan LiuDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Zi-En HuangDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Ting-Ting WeiDepartment of Laboratory, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Ying-Fen QinDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Zhen-Xing HuangDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Hai-Yan YangDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
Shan-Shan LanDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China.
De-Cheng LuDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China. 237540679@qq.com.
Zuo-Jie LuoDepartment of Endocrinology, The First Affiliated Hospital of Guangxi Medical University, No.6 Shuang Yong Road, Nanning, 530021, China. luozuojie@gxmu.edu.cn.ORCID 0000-0003-2969-8329

Funding

Ministry of Science and Technology of the People's Republic of China 2016YFC0901205National Natural Science Foundation of China 82260159
6 · The paper itself

Abstract

Thyroid hormones (THs) may affect chronic thyrotoxic myopathy (CTM). The relationship between TH sensitivity and CTM is inconsistent. We aimed to investigate the associations between TH sensitivity and the risk of CTM and to screen potential CTMs with strength and function tests. A total of 162 Chinese patients (36.58% men) with Graves' disease were enrolled and divided into CTM and non-CTM groups. TH and sensitivity indices were measured. Muscle power and function were assessed by grip, upper-limb fatigue (ULFT), lower-limb fatigue (LLFT), and squat-up (SUT) tests, and walking pace. Association between sensitivity to TH indices and the risk of developing CTM was assessed via multivariate logistic regression. The diagnostic effectiveness of muscle power and function for predicting CTM was evaluated via receiver operating characteristic (ROC) curves. Thyroid feedback quantile-based index FT

Indexed as

Graves DiseaseThyroid HormonesAdultFatigueFemaleHumansLower ExtremityMaleMiddle AgedMuscular DiseasesROC CurveThyroid Function TestsThyrotoxicosisThyroid HormonesChronic thyrotoxic myopathyGraves’ diseaseSensitivity to thyroid hormonesSkeletal muscle

Identifiers

PMID39420080
PMCPMC11487120

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.