Evidence map›Paper›PMID 39419934›Full record

ArticleMonash bioethics review2024

Antibiotic prescription, dispensing and use in humans and livestock in East Africa: does morality have a role to play?

Edna Mutua, A Davis, E Laurie, T Lembo, M Melubo, K Mnzava, E Msoka, F Nasua, T Ndibohoye, R Zadoks and 2 more

Abstract read
In one paragraph

Article in Monash bioethics review, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Edna Mutua *School of Social and Political Sciences, School of Health and Wellbeing, University of Glasgow, 11 Chapel Lane, Glasgow, G11 6EW, UK. ednamutua@gmail.com.ORCID http://orcid.org/0000-0002-7511-9116
A Davis *School of Social and Political Sciences, School of Health and Wellbeing, University of Glasgow, 11 Chapel Lane, Glasgow, G11 6EW, UK.
E LaurieSchool of Geographical and Earth Sciences, University of Glasgow, Glasgow, UK.
T LemboThe Boyd Orr Centre for Population and Ecosystem Health, Institute of Bioaffiliationersity, Animal Health & Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
M MeluboKilimanjaro Christian Medical Centre/Kilimanjaro, Kilimanjaro Clinical Research Institute, Christian Medical University College, Moshi, Tanzania.
K MnzavaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences/Bugando Medical Centre, Mwanza, Tanzania.
E MsokaKilimanjaro Christian Medical Centre/Kilimanjaro, Kilimanjaro Clinical Research Institute, Christian Medical University College, Moshi, Tanzania.
F NasuaKilimanjaro Christian Medical Centre/Kilimanjaro, Kilimanjaro Clinical Research Institute, Christian Medical University College, Moshi, Tanzania.
T NdibohoyeDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences/Bugando Medical Centre, Mwanza, Tanzania.
R ZadoksUniversity of Sydney, Sydney, Australia.
B MmbagaKilimanjaro Christian Medical Centre/Kilimanjaro, Kilimanjaro Clinical Research Institute, Christian Medical University College, Moshi, Tanzania.
S MshanaDepartment of Microbiology and Immunology, Catholic University of Health and Allied Sciences/Bugando Medical Centre, Mwanza, Tanzania.

Funding

Medical Research Council MRC/AMR/ MR/S004815/1Medical Research Council MR/S004815/1
6 · The paper itself

Abstract

backgroundAntimicrobial resistance (AMR) is a global threat to human and livestock health. Although AMR is driven by use of antimicrobials, it is often attributed to "misuse" and "overuse", particularly for antibiotics. To curb resistance, there has been a global call to embrace new forms of moral personhood that practice "proper" use, including prescription, dispensing and consumption of antimicrobials, especially antibiotics. This paper seeks to reflect on complex questions about how morality has become embedded /embodied in the AMR discourse as presented in the data collected on antimicrobial prescription, dispensing and use in human and livestock health in Tanzania, primarily focusing on antibiotics.

methodsThis reflection is anchored on Jarrett Zigon's morality framework that is comprised of three dimensions of discourse; the institutional, public, and embodied dispositions. The data we use within this framework are derived from a qualitative study targeting human and animal health care service providers and community members in northern Tanzania. Data were collected through 28 in-depth interviews and ten focus group discussions and analysed through content analysis after translation and transcription. In addition, a review of the Tanzania's National Action Plans on antimicrobial resistance was conducted.

resultsApplication of the framework demonstrates points of convergence and divergence in the institutional morality discourse articulated by the Tanzania National Action Plans, the public discourse and the embodied dispositions/ lived experiences of human and animal health care service providers and community members. We demonstrate that AMR is not just associated with "inappropriate" behaviour on the part of drug prescribers, dispensers, and users but also with shortcomings in health systems and service delivery.

conclusionAntibiotic dispensing and use practices that may be associated with the development of AMR should not be viewed in isolation from the broader health context within which they occur.

Indexed as

Anti-Bacterial AgentsDrug PrescriptionsMoralsAnimalsHumansLivestockTanzaniaAnti-Bacterial AgentsAntimicrobial resistanceEast AfricaHealth systemsMoralityOne health

Identifiers

PMID39419934
PMCPMC11850405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.