Evidence map›Paper›PMID 39419896›Full record

ReviewJournal of fluorescence2025

Effective Determination of Diosmin Using Nitrogen Doped Carbon Dots as Probe Based on Internal Filtering Effect.

Xian Chen, Menghan Zhang, Lang Zheng, Xiaoqin Deng, Qiang Chen, Wendi Han, Zhengjun Huang, Shaohuang Weng

Abstract readReview
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In one paragraph

Review in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xian ChenDepartment of Pharmacy, Xiamen Humanity Hospital Affiliated to Fujian Medical University, Xiamen, 361016, China.
Menghan ZhangDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Lang ZhengDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Xiaoqin DengDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.
Qiang ChenDepartment of Andrology & Sexual Medicine, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China. fjykdxfynk@126.com.
Wendi HanDepartment of Pharmacy, First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Zhengjun HuangDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China. jjonepo@163.com.
Shaohuang WengDepartment of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The establishment of a convenient and efficient testing method is crucial and needed for the monitoring of diosmin. In this study, nitrogen doped carbon dots (N-CDs) with the particle size distribution of 2.5-5.7 nm and the average diameter of 4.1 nm were successfully synthesized using a simple strategy. N-CDs exhibited excellent and stable fluorescence performance with the quantum yield of 22.33%. Correspondingly, a fluorescence analytical method was developed for diosmin determination using N-CDs as probe. UV-vis absorbance spectroscopy and the evaluation of internal filtering parameters verified that the mechanism causing the quenching of N-CDs was an internal filtering effect (IFE). The concentration of diosmin can be directly evaluated based on the quenched fluorescence intensities. After optimizing experimental conditions, it was found that the fluorescence quenching efficiency ((F

Indexed as

CarbonDiosminFluorescent DyesNitrogenQuantum DotsHumansLimit of DetectionParticle SizeSpectrometry, FluorescenceTabletsCarbonDiosminFluorescent DyesNitrogenTabletsDiosminDrug monitoringFluorescence analysis methodInternal filtering effectNitrogen doped carbon dots

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.