Evidence map›Paper›PMID 39419503›Full record

ArticleJournal of medicinal chemistry2024

Structure-Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT.

Marie Wannowius, Christopher Neelen, Philipp Lotz, Michael Daude, Anita Neubauer, Bärbel Fühler, Wibke E Diederich, Joachim Geyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marie WannowiusInstitute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Biomedical Research Center Seltersberg (BFS), Justus Liebig University of Giessen, Schubertstr. 81, Giessen 35392, Germany.
Christopher NeelenInstitute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Biomedical Research Center Seltersberg (BFS), Justus Liebig University of Giessen, Schubertstr. 81, Giessen 35392, Germany.
Philipp LotzDepartment of Medicinal Chemistry and Core Facility Medicinal Chemistry, Center for Tumor- and Immune Biology, Philipps University Marburg, Hans-Meerwein-Str. 3, Marburg 35043, Germany.
Michael DaudeDepartment of Medicinal Chemistry and Core Facility Medicinal Chemistry, Center for Tumor- and Immune Biology, Philipps University Marburg, Hans-Meerwein-Str. 3, Marburg 35043, Germany.
Anita NeubauerInstitute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Biomedical Research Center Seltersberg (BFS), Justus Liebig University of Giessen, Schubertstr. 81, Giessen 35392, Germany.
Bärbel FühlerInstitute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Biomedical Research Center Seltersberg (BFS), Justus Liebig University of Giessen, Schubertstr. 81, Giessen 35392, Germany.
Wibke E DiederichDepartment of Medicinal Chemistry and Core Facility Medicinal Chemistry, Center for Tumor- and Immune Biology, Philipps University Marburg, Hans-Meerwein-Str. 3, Marburg 35043, Germany.ORCID 0000-0001-5671-6575
Joachim GeyerInstitute of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Biomedical Research Center Seltersberg (BFS), Justus Liebig University of Giessen, Schubertstr. 81, Giessen 35392, Germany.ORCID 0000-0003-2663-1858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal bile acid carrier ASBT (

Indexed as

Organic Anion Transporters, Sodium-DependentSymportersAnilidesAnimalsBenzamidesHumansStructure-Activity RelationshipAnilidesBenzamidesbenzanilideOrganic Anion Transporters, Sodium-Dependentsodium-bile acid cotransporterSymporters

Identifiers

PMID39419503
PMCPMC11571210

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.