Evidence map›Paper›PMID 39419099›Full record

ReviewEuropean thyroid journal2024

Management of follicular thyroid carcinoma.

Haruhiko Yamazaki, Kiminori Sugino, Ryohei Katoh, Kenichi Matsuzu, Wataru Kitagawa, Mitsuji Nagahama, Aya Saito, Koichi Ito

Abstract readReview
In one paragraph

Review in European thyroid journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haruhiko YamazakiDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama City, Kanagawa, Japan.ORCID 0000-0002-6640-3529
Kiminori SuginoDepartment of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan.
Ryohei KatohDepartment of Pathology, Ito Hospital, Shibuya-ku, Tokyo, Japan.
Kenichi MatsuzuDepartment of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan.
Wataru KitagawaDepartment of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan.
Mitsuji NagahamaDepartment of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan.
Aya SaitoDepartment of Surgery, Yokohama City University School of Medicine, Yokohama City, Kanagawa, Japan.
Koichi ItoDepartment of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular thyroid carcinoma (FTC) is the second most common histological type of thyroid carcinoma. This review aims to summarize the available evidence and guidelines and provide an updated consensus regarding the management of FTC. The cytoarchitectural features of FTC are similar to those of follicular adenoma (FA), and it is difficult to preoperatively distinguish between FA and FTC. For nodules with Bethesda class III-V cytology, molecular test results (if available) should be considered before the operation. However, it should be noted that molecular tests are not available in all countries. The goals of initial surgical therapy for patients with FTC are to improve overall and disease-specific survival, reduce the risk of persistent/recurrent disease and associated morbidity, and permit accurate disease staging and risk stratification while minimizing treatment-related morbidity and unnecessary therapy. Previous studies have reported some prognostic factors such as distant metastasis, age, tumor size, vascular invasion, TERT promoter mutation, and histological subtype. In particular, the degree of vascular invasion is becoming increasingly important. Evaluating these prognostic factors is essential for prognostic prediction and precise management of patients with FTC. Recurrence and distant metastasis of FTC are treated with radioactive iodine (RAI). However, some FTCs become refractory to RAI. Multi-tyrosine kinase inhibitors such as sorafenib and lenvatinib are utilized for treating RAI-refractory FTCs. In addition, given that renin-angiotensin system (RAS) is the most common driver gene for FTC, it is also important to develop RAS inhibitors.

Indexed as

Adenocarcinoma, FollicularThyroid NeoplasmsHumansIodine RadioisotopesNeoplasm Recurrence, LocalPhenylurea CompoundsPrognosisProtein Kinase InhibitorsSorafenibThyroidectomyIodine RadioisotopesPhenylurea CompoundsProtein Kinase InhibitorsSorafenibdifferentiated thyroid cancerthyroid cancerthyroidectomy

Identifiers

PMID39419099
PMCPMC11558955

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.