Evidence map›Paper›PMID 39418993›Full record

ArticleInternational journal of surgery case reports2024

Orbital leiomyoma originating from Muller muscle: A case report and review of the literature.

Rakan Alsaad, Hind M Alkatan, Hatim Khoja, Adel Alsuhaibani

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Article in International journal of surgery case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Rakan AlsaadDepartment of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Hind M AlkatanDepartment of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia; Department of Pathology and Laboratory Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia. Electronic address: hkatan@ksu.edu.sa.
Hatim KhojaAnatomic Pathology Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. Electronic address: hkhoja@kfshrc.edu.sa.
Adel AlsuhaibaniDepartment of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOrbital leiomyoma can occur anywhere within the orbit. Posterior tumors arise from vessel wall smooth muscle cells, while anterior tumors develop from the capsulopalpebral or Muller muscle. PRESENTATION OF CASE: we present a case of a 24-year-old man who was referred for evaluation of chronic right eye swelling involving the medial upper eyelid. Ophthalmologic examination was unremarkable apart from upper lid fullness along with downward and lateral displacement of the globe. MRI revealed a large and well-defined growth in the right medial orbital space. An excisional biopsy was performed which showed a friable mass strongly adherent to the underlying conjunctiva and Muller muscle. This case report has been prepared and reported in line with the SCARE criteria. DISCUSSION: Orbital leiomyoma usually presents with progressive painless proptosis if situated deep in the orbit. Our patient presented mainly with eyelid fullness and displacement due to the anterior location of his tumor. The diagnosis of orbital leiomyoma has to be confirmed by histopathological and immunohistochemical assessments such as in our case. A literature review was conducted using multiple databases spanning from 1963 to 2023 which concluded male predominance. One similar case to ours has been reported with the tumor originating from supraorbital neurovascular bundle.

conclusionTo the best of our knowledge, this is the first reported case of an orbital leiomyoma originating from the Muller muscle in the English literature.

Indexed as

HistopathologyLeiomyomaMüller's muscleOrbitSmooth muscle

Identifiers

PMID39418993
PMCPMC11532450

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