ArticleBiomaterials2025
PAR
Abstract read
In one paragraph
Article in Biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Dual-Targeted Inhibition of PARNanomaterials (Basel, Switzerland) · 2026Article
- Applications of micro/nano drug delivery systems in cancer pain management.Bioactive materials · 2026Review
- MMP1 and PRSS23 induce PARCommunications biology · 2026Article
- Targeting CGRP signaling alleviates cancer-associated pain in oral squamous cell carcinoma.BMC oral health · 2026Article
- Protease-Activated Receptor-2 Promotes Metastasis: An Emerging Therapeutic Target.Molecular cancer research : MCR · 2026Review
- Nanoparticle-mediated antagonism of sustained endosomal signaling of the calcitonin receptor-like receptor provides enhanced and persistent relief of oral cancer pain.Biomaterials · 2026Article
- Review
- Pharmacological Management of Cancer Pain: Advances in Treatment Strategies and Drug Delivery Systems.Pharmaceutics · 2025Review
- Synergistic effects of PAR2 and TrkA exacerbate visceral hypersensitivity induced by chronic pancreatitis in rats.IBRO neuroscience reports · 2025Article
- Reprogramming neural-tumor crosstalk: emerging therapeutic dimensions and targeting strategies.Military Medical Research · 2025Review
- Emerging therapeutic approaches for treating abdominal pain.Journal of the Canadian Association of Gastroenterology · 2025Review
- Construction of an immune prediction model for osteosarcoma based on coagulation-related genes.Discover oncology · 2025Article
- Investigating the potential role of EIF2S2 in OSCC progression through comprehensive bioinformatics analysis and experimental validation.European journal of medical research · 2025Article
- Pain Signaling by GPCRs and RTKs.Trends in pharmacological sciences · 2025Review
- Engineering Nanoscale Drug Delivery Systems for Pain.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Divya BhansaliDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA. Electronic address: divya.bhansali@columbia.edu.
Nguyen H TuNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA; Pain Research Center, New York University, New York, NY, 10010, USA. Electronic address: n.h.tu@nyu.edu.
Kenji InoueNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA; Pain Research Center, New York University, New York, NY, 10010, USA. Electronic address: ki630@nyu.edu.
Shavonne TengPain Research Center, New York University, New York, NY, 10010, USA; Department of Molecular Pathobiology, New York University Dentistry, New York, NY, 10010, USA; Department of Physiology and Cellular Biophysics, Columbia University Irving Medical Center, New York, NY, 10032, USA. Electronic address: st2741@cumc.columbia.edu.
Tianyu LiDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA. Electronic address: lity@ipe.ac.cn.
Hung D TranNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA. Electronic address: hdt222@nyu.edu.
Dong H KimNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA. Electronic address: dhk422@nyu.edu.
Jessy DongNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA. Electronic address: jd2693@nyu.edu.
Chloe J PeachPain Research Center, New York University, New York, NY, 10010, USA; Department of Molecular Pathobiology, New York University Dentistry, New York, NY, 10010, USA; Centre of Membrane Proteins and Receptors, School of Life Sciences, Queen's Medical Centre, University of Nottingham, UK. Electronic address: chloe.peach2@nottingham.ac.uk.
Badr SokratPain Research Center, New York University, New York, NY, 10010, USA; Department of Molecular Pathobiology, New York University Dentistry, New York, NY, 10010, USA. Electronic address: bs5078@nyu.edu.
Dane D JensenNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA; Pain Research Center, New York University, New York, NY, 10010, USA. Electronic address: ddj3@nyu.edu.
John C DolanNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA. Electronic address: jcd10@nyu.edu.
Seiichi YamanoDepartment of Prosthodontics, New York University Dentistry, New York, NY, 10010, USA. Electronic address: sy23@nyu.edu.
Valeria Mezzano RobinsonDepartment of Pathology, New York University Grossman School of Medicine, New York, NY, 10016, USA. Electronic address: valeria.mezzanorobinson@nyulangone.org.
Nigel W BunnettPain Research Center, New York University, New York, NY, 10010, USA; Department of Molecular Pathobiology, New York University Dentistry, New York, NY, 10010, USA; Neuroscience Institute, New York University Langone Health, New York, NY, 10016, USA; Department of Neuroscience and Physiology, New York University Grossman School of Medicine, New York, NY, 10016, USA. Electronic address: nwb2@nyu.edu.
Donna G AlbertsonNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA; Pain Research Center, New York University, New York, NY, 10010, USA. Electronic address: da66@nyu.edu.
Kam W LeongDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA. Electronic address: kwl2121@columbia.edu.
Brian L SchmidtNew York University Dentistry Translational Research Center, New York University Dentistry, New York, NY, 10010, USA; Pain Research Center, New York University, New York, NY, 10010, USA; Department of Neuroscience and Physiology, New York University Grossman School of Medicine, New York, NY, 10016, USA. Electronic address: bls322@nyu.edu.
Funding
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1MTR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3MEndosomal mechanisms signaling oral cancer painRM1DE033491 · NIDCR · NEW YORK UNIVERSITY · PI NIGEL W BUNNETT, Rajesh Khanna · 2023 to 2026
$6.4MTargeting Endosomal Receptors for Treatment of Chronic PainR01DE029951 · NIDCR · NEW YORK UNIVERSITY · PI BUNNETT, NIGEL W, SCHMIDT, BRIAN L · 2020 to 2024
$4.7MProtease/PAR2/TRPV4 Axis and Oral Cancer PainR01DE026806 · NIDCR · NEW YORK UNIVERSITY · PI BUNNETT, NIGEL W, SCHMIDT, BRIAN L · 2018 to 2022
$3.9MEndosomal Platforms for Signaling PainR01NS102722 · NINDS · NEW YORK UNIVERSITY · PI NIGEL W BUNNETT, Brian L Schmidt · 2017 to 2026
$3.4MTRPV1 nociceptors in oral carcinogenesis and painR01CA231396 · NCI · NEW YORK UNIVERSITY · PI ALBERTSON, DONNA G, SCHMIDT, BRIAN L · 2021 to 2025
$3.1MIntratumor co-delivery of DNA and RNA to relieve cancer painR01DE029694 · NIDCR · NEW YORK UNIVERSITY · PI SCHMIDT, BRIAN L, YAMANO, SEIICHI · 2021 to 2025
$2.9MArtemin overexpression in oral cancer pain and carcinogenesisR01CA228525 · NCI · NEW YORK UNIVERSITY · PI ALBERTSON, DONNA G, SCHMIDT, BRIAN L · 2019 to 2024
$2.6MMultispectral imaging & analysis of intact tissue sections w/ the Perkin Elmer VectraS10OD021747 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LOOMIS, CYNTHIA A · 2016 to 2016
$359kEndosomal Signaling of PAR2 in Oral Cancer PainF31DE031178 · NIDCR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TENG, SHAVONNE · 2021 to 2023
$143kNCI NIH HHS P30 CA016087NCI NIH HHS R01 CA228525NCI NIH HHS R01 CA231396NIBIB NIH HHS P41 EB017183NIDCR NIH HHS F31 DE031178NIDCR NIH HHS R01 DE026806NIDCR NIH HHS R01 DE029694NIDCR NIH HHS R01 DE029951NIDCR NIH HHS RM1 DE033491NIH HHS S10 OD021747NINDS NIH HHS R01 NS102722
Abstract
Oral cancer is notoriously painful. Activation of protease-activated receptor 2 (PAR
Indexed as
Cancer PainMouth NeoplasmsNanoparticlesNociceptorsReceptor, PAR-2AnimalsCell Line, TumorHumansMaleMiceMice, Inbred C57BLF2RL1 protein, humanReceptor, PAR-2NanoparticlesOral cancerOral cancer painPAR(2)Protease-activated receptor 2
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.