Evidence map›Paper›PMID 39418186›Full record

ReviewRadiographics : a review publication of the Radiological Society of North America, Inc2024

Pediatric Diffuse Lung Disease in Infants: Imaging Findings and Histopathologic Correlation.

Karen I Ramirez-Suarez, Santiago Martinez-Correa, Luis O Tierradentro-Garcia, Ammie M White, Mariangeles Medina Perez, Hansel J Otero, David M Biko, Lisa R Young, Jennifer Pogoriler, John P Lichtenberger and 1 more

Abstract readReview
In one paragraph

Review in Radiographics : a review publication of the Radiological Society of North America, Inc, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. [Childhood interstitial lung disease].Radiologie (Heidelberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Karen I Ramirez-SuarezFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0002-5613-162X
Santiago Martinez-CorreaFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0009-0002-8786-0224
Luis O Tierradentro-GarciaFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0003-1164-4656
Ammie M WhiteFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0001-8949-2539
Mariangeles Medina PerezFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0001-6293-9900
Hansel J OteroFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0003-4626-0732
David M BikoFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0002-0598-2205
Lisa R YoungFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).
Jennifer PogorilerFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0001-9366-4401
John P LichtenbergerFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0002-6438-343X
Jordan B RappFrom the Department of Radiology (K.I.R.S., S.M.C., L.O.T.G., A.M.W., M.M.P., H.J.O., D.M.B., L.R.Y., J.B.R.) and Division of Anatomic Pathology (J.P.), Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa (L.O.T.G., A.M.W., H.J.O., D.M.B., L.R.Y., J.P., J.B.R.); Department of Radiology, University of Alabama at Birmingham, Birmingham, Ala (M.M.P.); American College of Radiology Institute of Radiologic Pathology, Silver Spring, Md (D.M.B., J.P.L.); and George Washington University Hospital, Washington, DC (J.P.L.).ORCID 0000-0002-5956-1975

Funding

Midcareer Investigator Award in Patient-Oriented Research in Pediatric Rare Lung DiseasesK24HL143281 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI YOUNG, LISA R. · 2018 to 2022
$540k
NHLBI NIH HHS K24 HL143281
6 · The paper itself

Abstract

Childhood interstitial lung disease (chILD) encompasses a diverse group of genetic, infectious, and inflammatory conditions affecting infants and children. The recognition and understanding of these entities have highlighted the necessity for more accurate classification. This group of rare heterogeneous diseases comprises more than 200 different conditions and has a combined estimated prevalence of less than one patient per 100 000 children. Hence, a systematic diagnostic approach is crucial. This article describes a diagnostic approach for pediatric diffuse lung diseases in infancy, including an analysis of clinical presentations and imaging and histologic features to effectively distinguish among various chILD entities. Although they often have overlapping and nonspecific radiologic features, some chILD entities may exhibit typical imaging findings, resulting in a CT diagnosis or aiding in narrowing the differential diagnosis, thus guiding the clinician to the appropriate genetic tests, potentially limiting unnecessary biopsies. This approach aims to enhance the understanding and diagnosis of chILD in infants, thereby facilitating improved patient care.

Indexed as

Lung Diseases, InterstitialTomography, X-Ray ComputedDiagnosis, DifferentialFemaleHumansInfantInfant, NewbornMale

Identifiers

PMID39418186
PMCPMC11580020

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.