Evidence map›Paper›PMID 39418094›Full record

ArticleJMIR formative research2024

Phenotyping Adherence Through Technology-Enabled Reports and Navigation (the PATTERN Study): Qualitative Study for Intervention Adaptation Using the Exploration, Preparation, Implementation, and Sustainment Framework.

Allison P Pack, Stacy C Bailey, Rachel O'Conor, Evelyn Velazquez, Guisselle Wismer, Fangyu Yeh, Laura M Curtis, Kenya Alcantara, Michael S Wolf

Abstract read
In one paragraph

Article in JMIR formative research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Allison P PackDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-5802-293X
Stacy C BaileyDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-2566-3789
Rachel O'ConorDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-5104-9531
Evelyn VelazquezDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0009-0000-2541-6676
Guisselle WismerDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-2407-662X
Fangyu YehDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0001-7502-1218
Laura M CurtisDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0003-2380-2201
Kenya AlcantaraDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0009-0005-3788-561X
Michael S WolfDivision of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.ORCID 0000-0002-4342-6517

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
The Claude D. Pepper Older Americans Independence Center (OAIC) at Northwestern UniversityP30AG059988 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ACKERMANN, RONALD T. · 2020 to 2024
$7.1M
NCATS NIH HHS UL1 TR001422NIA NIH HHS P30 AG059988
6 · The paper itself

Abstract

backgroundOlder adults with multiple chronic conditions (MCC) and polypharmacy often face challenges with medication adherence. Nonadherence can lead to suboptimal treatment outcomes, adverse drug events, and poor quality of life.

objectiveTo facilitate medication adherence among older adults with MCC and polypharmacy in primary care, we are adapting a technology-enabled intervention previously implemented in a specialty clinic. The objective of this study was to obtain multilevel feedback to inform the adaptation of the proposed intervention (Phenotyping Adherence Through Technology-Enabled Reports and Navigation [PATTERN]).

methodsWe conducted a formative qualitative study among patients, clinicians, and clinic administrators affiliated with a large academic health center in Chicago, Illinois. Patient eligibility included being aged 65 years or older, living with MCC, and contending with polypharmacy. Eligibility criteria for clinicians and administrators included being employed by any primary care clinic affiliated with the participating health center. Individual semistructured interviews were conducted remotely by a trained member of the study team using interview guides informed by the Exploration, Preparation, Implementation, and Sustainment Framework. Thematic analysis of interview audio recordings drew from the Rapid Identification of Themes from Audio Recordings procedures.

resultsIn total, we conducted 25 interviews, including 12 with clinicians and administrators, and 13 with patients. Thematic analysis revealed participants largely found the idea of technology-based medication adherence monitoring to be acceptable and appropriate for the target population in primary care, although several concerns were raised; we discuss these in detail.

conclusionsOur medication adherence monitoring intervention, adapted from specialty care, will be implemented in primary care. Formative interviews, informed by the Exploration, Preparation, Implementation, and Sustainment Framework and conducted among patients, clinicians, and administrators, have identified intervention adaptation needs. Results from this study could inform other interventions using the patient portal with older adults.

Indexed as

Medication AdherenceQualitative ResearchAgedAged, 80 and overChicagoFemaleHumansMaleMultiple Chronic ConditionsPolypharmacyintervention developmentmedication adherenceolder adultspolypharmacyqualitative research

Identifiers

PMID39418094
PMCPMC11528165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.