Evidence map›Paper›PMID 39418040›Full record

SynthesisJAMA ophthalmology2024

Prevalence of Glaucoma Among US Adults in 2022.

Joshua R Ehrlich, Zeb Burke-Conte, John S Wittenborn, Jinan Saaddine, John D Omura, David S Friedman, Abraham D Flaxman, David B Rein

Abstract readMeta-Analysis
In one paragraph

Synthesis in JAMA ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed.

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  3. Patterns of Glaucoma Treatment Use in Asian American Patients With Primary Open-Angle Glaucoma.Mayo Clinic proceedings. Innovations, quality & outcomes · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Joshua R EhrlichDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor.
Zeb Burke-ConteInstitute for Health Metrics and Evaluation, University of Washington, Seattle.
John S WittenbornNORC @ the University of Chicago, Chicago, Illinois.
Jinan SaaddineDivision of Diabetes Translation, Vision Health Initiative, Centers for Disease Control and Prevention, Atlanta, Georgia.
John D OmuraDivision of Diabetes Translation, Vision Health Initiative, Centers for Disease Control and Prevention, Atlanta, Georgia.
David S FriedmanGlaucoma Center of Excellence, Massachusetts Eye and Ear, Harvard University, Boston.
Abraham D FlaxmanInstitute for Health Metrics and Evaluation, University of Washington, Seattle.
David B ReinNORC @ the University of Chicago, Chicago, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Glaucoma is the leading cause of irreversible blindness worldwide and, in the US, disproportionately affects people from racial and ethnic minority groups. Glaucoma prevalence has not been estimated for the US in more than a decade, and state- and county-level estimates are not available. Objective: To estimate glaucoma and vision-affecting glaucoma prevalence by demographic factors and US state and county for the Centers for Disease Control and Prevention's Vision and Eye Health Surveillance System (VEHSS). Data Sources: This meta-analysis used data from the National Health and Nutrition Examination Survey (2005-2008), Medicare fee-for-service claims (2019), IBM MarketScan commercial insurance claims (2016), population-based studies of eye disease (1985-2003), and 2022 population estimates from the US Census Bureau. Study Selection: PubMed was searched for population-based studies of glaucoma prevalence published between 1991 and 2016. Data Extraction and Synthesis: Bayesian meta-regression methods were used to estimate the prevalence of glaucoma and vision-affecting glaucoma stratified by age, undifferentiated sex/gender (a measure that captures an unclear mix of aspects of sex and or gender), race and ethnicity, and US county and state. Main Outcomes and Measures: Prevalence of any type of glaucoma (open or closed angle) among people 18 years or older and vision-affecting glaucoma, defined as glaucoma and a visual field abnormality. Results: For 2022, an estimated 4.22 million people (95% uncertainty interval [UI], 3.46 million to 5.23 million) in the US were living with glaucoma, with a prevalence of 1.62% (UI, 1.33%-2.00%) among people 18 years or older and 2.56% (UI, 2.10%-3.16%) among people 40 years or older. An estimated 1.49 million people (UI, 1.17 million to 1.90 million) were living with vision-affecting glaucoma, with a prevalence of 0.57% (UI, 0.45%-0.73%) among people 18 years or older and 0.91% (UI, 0.71%-1.16%) among people 40 years or older. Prevalence of glaucoma among people 18 years or older ranged from 1.11% (UI, 0.89%-1.40%) in Utah to 1.95% (UI, 1.57%-2.39%) in Mississippi. Black adults had a prevalence of 3.15% (UI, 2.32%-4.09%) compared with 1.42% (UI, 1.10%-1.85%) among White adults; adults in the Hispanic and all other racial and ethnic categories combined had a prevalence of 1.56% (UI, 1.13%-2.06%). Conclusions and Relevance: This meta-analysis found that an estimated 2.56% of people 40 years or older have glaucoma, slightly more than estimated by previous studies. Black individuals are disproportionately affected. Prevalence estimates at the state and county level can help guide public health planning.

Indexed as

GlaucomaAdultAgedAged, 80 and overAge DistributionFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceSex DistributionUnited States

Identifiers

PMID39418040
PMCPMC11581589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.