Evidence map›Paper›PMID 39417926›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Extracorporeal cytokine adsorption as therapeutic option for immune effector cell-associated neurotoxicity syndrome.

Alix Buhlmann, Emanuel Rom, Giovanna Schweiger, Dominik Schneidawind, Sascha David

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PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alix Buhlmann *Institute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, Zurich, 8091, Switzerland.
Emanuel Rom *Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.
Giovanna SchweigerInstitute of Anesthesiology, University Hospital Zurich, Zurich, Switzerland.
Dominik SchneidawindDepartment of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.
Sascha DavidInstitute of Intensive Care Medicine, University Hospital Zurich, Rämistrasse 100, Zurich, 8091, Switzerland. sascha.david@usz.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the rising number of patients receiving chimeric antigen receptor T-cells, the treatment of this therapy's complications is of growing concern to intensivists and neurologists. We used extracorporeal cytokine adsorption as an add-on therapy in a patient suffering from immune effector cell-associated neurotoxicity syndrome. Interleukin-6 level, which as a readily available parameter is generally used to evaluate course of disease, was rapidly reduced using this method. The patient made a full recovery and is still in hematological remission.

Indexed as

CytokinesNeurotoxicity SyndromesFemaleHumansImmunotherapy, AdoptiveInterleukin-6Malecell-associated neurotoxicityCytokinesInterleukin-6Blood PurificationClearanceHemoperfusionRemoval

Identifiers

PMID39417926
PMCPMC11698748

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