Evidence map›Paper›PMID 39417863›Full record

ArticleEuropean journal of applied physiology2025

Are females getting more fatigable as they age?

Mathilde Fiona Bertrand, Giorgio Varesco, Guillaume Y Millet, Léonard Féasson, Thomas Lapole, Vianney Rozand

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Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mathilde Fiona BertrandLaboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.ORCID http://orcid.org/0009-0002-0920-204X
Giorgio VarescoDepartment of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.ORCID http://orcid.org/0000-0001-9385-6972
Guillaume Y MilletLaboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.ORCID http://orcid.org/0000-0002-6395-0762
Léonard FéassonLaboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.ORCID http://orcid.org/0000-0002-8163-5539
Thomas LapoleLaboratoire Interuniversitaire de Biologie de la Motricité, Université Jean Monnet Saint-Etienne, Lyon 1, Université Savoie Mont-Blanc, 42023, Saint-Etienne, France.ORCID http://orcid.org/0000-0002-1477-6614
Vianney RozandCAPS, Inserm UMR1093, UFR des Sciences du Sport, Faculté des Sciences du Sport, Université de Bourgogne, BP 27877, 21078, Dijon, France. vianney.rozand@u-bourgogne.fr.ORCID http://orcid.org/0000-0002-7479-1189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to compare performance fatigability between young (n = 13; 18-35 yr.; 23.5 ± 3.3 yr.), old (n = 13; 60-79 yr.; 68.2 ± 4.3 yr.), and very old (n = 11; ≥ 80 yr.; 85.6 ± 1.8 yr.) females during single-limb isometric (ISO) vs. isokinetic concentric (CON) vs. cycling (BIKE) fatiguing tasks.

methodsParticipants randomly performed three incremental fatiguing tasks where increments were set as percentage of body weight to better reflect the daily life: (1) ISO and (2) CON consisted of stages of 75 contractions (120 s, 0.8 s on/0.8 s off) on an isokinetic dynamometer and (3) BIKE consisted of stages of 120 s at 37.5 rpm with similar duty cycle. Knee extensors maximal force, voluntary activation and potentiated twitch amplitude were measured at baseline, after each stage and at exhaustion.

resultsCompared to young, exercise performance was 20% and 53% lower in old and very old females in ISO, 46% and 76% lower in CON and 32% and 62% lower in BIKE (all p < 0.01). For a given workload (i.e. common stages), performance fatigability (i.e. force loss) was greater for very old compared to young females in CON only (p = 0.018). At exhaustion, performance fatigability was similar across groups and conditions (~ 30%; all p > 0.05), with similar impairments in both voluntary activation and twitch amplitude.

conclusionThese results emphasize the importance of the kind of fatiguing task and modalities of evaluation when investigating the effects of aging on performance fatigability.

Indexed as

AgingMuscle FatigueMuscle, SkeletalAdolescentAdultAgedAged, 80 and overFemaleHumansIsometric ContractionMiddle AgedYoung AdultAgingFatiguing tasksKnee extensorsPerformance fatigability

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.