Evidence map›Paper›PMID 39417617›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2025

On role models and Joe LeDoux.

Sheena A Josselyn

Abstract readHistorical Article
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sheena A JosselynProgram in Neurosciences & Mental Health, Hospital for Sick Children, 555 University Ave., Toronto, ON M5G 1X8, Canada.ORCID 0000-0001-5451-489X

Funding

The Role of Neuronal Ensembles Supporting Auditory Fear Conditioning (Engrams) in the Amygdala in Memory Formation, Generalization and ExtinctionR01MH119421 · NIMH · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI FRANKLAND, PAUL, JOSSELYN, SHEENA A · 2019 to 2023
$1.7M
Brain Canada FoundationCIHR FDN-159919NIMH NIH HHS R01 MH119421NIMH NIH HHS R01 MH119421-01NSERC
6 · The paper itself

Abstract

Joseph LeDoux is a pioneering neuroscientist who has made profound discoveries that continue to impact our understanding of the neural basis of emotion and memory, particularly the role of the amygdala in threat conditioning. LeDoux's trailblazing and elegant studies were some of the first to examine the circuit basis of behavior. His work combined techniques to trace pathways into and out of the amygdala important for threat conditioning and related behaviors. Since that time, these types of circuit tracing studies have exploded in popularity across neuroscience, and I would argue, we all owe a debt to LeDoux for this. LeDoux has made numerous additional contributions to neuroscience and, by bringing emotion back to neuroscience, has helped unite neuroscience with psychology. A gifted writer with a knack for communicating complicated scientific ideas in an accessible manner, LeDoux has become an ambassador of science who uses his love of music to help educate and inspire. Perhaps more important than these laudable scientific achievements, LeDoux is also a true "gentleman" of science, showing that science need not be a contact sport. Here, I give a personal account on why Joseph LeDoux is one of my scientific role models.

Indexed as

NeurosciencesAmygdalaEmotionsHistory, 20th CenturyHistory, 21st CenturyHumansamygdalaanxietyfearrodentrole modelthreat memory

Identifiers

PMID39417617
PMCPMC11712266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.