Evidence map›Paper›PMID 39417519›Full record

ArticleRevista de saude publica2024

Prep provision in community organizations: a comparative study with conventional services.

Alexandre Grangeiro, Paula Andrea Massa, Maria Mercedes Escuder, Eliana Miura Zucchi, Eliane Aparecida Sala, Eduardo Araujo de Oliveira, Raphaela Fini, Inês Dourado, Laio Magno, Beo Oliveira Leite and 4 more

Abstract readComparative Study
In one paragraph

Article in Revista de saude publica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alexandre GrangeiroUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-5157-0597
Paula Andrea MassaUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-8807-421X
Maria Mercedes EscuderSecretaria de Estado da Saúde de São Paulo. Instituto de Saúde. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-3103-2617
Eliana Miura ZucchiUniversidade Católica de Santos. Programa de Pós-Graduação em Saúde Coletiva. Santos, SP, Brasil.ORCID http://orcid.org/0000-0001-6234-1490
Eliane Aparecida SalaUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0009-0002-4194-4596
Eduardo Araujo de OliveiraUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0003-0866-2554
Raphaela FiniUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0009-0001-4063-2278
Inês DouradoUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.ORCID http://orcid.org/0000-0003-1675-2146
Laio MagnoUniversidade do Estado da Bahia. Departamento de Ciências da Vida. Salvador, BA, Brasil.ORCID http://orcid.org/0000-0003-3752-0782
Beo Oliveira LeiteUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil.ORCID http://orcid.org/0000-0002-4137-9809
Katia BruxvoortUniversity of Alabama at Birmingham. Birmingham, AL, United States of America.ORCID http://orcid.org/0000-0001-8277-2431
Sarah MacCarthyUniversity of Alabama at Birmingham. Birmingham, AL, United States of America.ORCID http://orcid.org/0000-0001-6468-8009
Marcia Thereza CoutoUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0001-5233-4190
Maria Fernanda Tourinho PeresUniversidade de São Paulo. Faculdade de Medicina. São Paulo, SP, Brasil.ORCID http://orcid.org/0000-0002-7049-905X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate whether adolescents from sexual minorities who initiated pre-exposure prophylaxis (PrEP) in community-based organizations (COs) are more socially and HIV-vulnerable compared with their counterparts from a conventional health service. In addition, to evaluate whether these adolescents had more timely access to prophylaxis.

methodsA PrEP demonstration study was conducted in the city of São Paulo in two COs, located in the center (CO-center) and the outskirts (CO-outskirts), and a conventional HIV testing service (CTA-center). Between 2020 and 2022, cisgender male adolescents who have sex with men (aMSM), transgender and gender diverse adolescents (aTTrans) aged 15 to 19 years, HIV-negative, with higher-risk practices for HIV were eligible for PrEP. Indicators of timely access and vulnerabilities of adolescents initiating PrEP in COs were analyzed using CTA-center as a reference and multinomial logistic regression.

results608 adolescents initiated PrEP in COs and CTA-center. Adolescents from COs were associated with a shorter time to PrEP initiation (1-7 days; CO-outskirts: ORa = 2.91; 95%CI 1.22-6.92; CO-center: ORa = 1.91; 95%CI 1.10-3.31); and a lower housing Human Development Index (HDI) (CO-center: ORa = 0.97; 95%CI 0.94-1.00; CO-outskirts: ORa = 0.82; 95%CI 0.78-0.86). In CO-outskirts, there was an increased chance of adolescents being younger (ORa = 3.06; 95%CI 1.63-5.75) and living closer to the service (ORa = 0.82; 95%CI 0.78-0.86, mean 7.8 km). While adolescents from the CO-center were associated with greater prior knowledge of PrEP (ORa = 2.01; 95%CI 1.10-3.91) and high-risk perception (ORa = 2.02; 95%CI 1.18-3.44), adolescents from the COs were not associated with higher-risk sexual practices and situations of vulnerability to HIV.

conclusionThe provision of PrEP in the COs facilitated access for vulnerable adolescents and may contribute to reducing inequities.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesAdolescentAnti-HIV AgentsBrazilCommunity Health ServicesFemaleHealth Services AccessibilityHomosexuality, MaleHumansMaleSocioeconomic FactorsYoung AdultAnti-HIV Agents

Identifiers

PMID39417519
PMCPMC11573378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.