Evidence map›Paper›PMID 39417162›Full record

ArticleCommunications materials2024

Design of stimuli-responsive minimalist heptad surfactants for stable emulsions.

Yang Li, Yilun Weng, Yue Hui, Jiaqi Wang, Letao Xu, Yang Yang, Guangze Yang, Chun-Xia Zhao

Abstract read
In one paragraph

Article in Communications materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang LiSchool of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.
Yilun WengAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD 4072 Australia.
Yue HuiSchool of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.
Jiaqi WangWisdom Lake Academy of Pharmacy, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123 China.
Letao XuSchool of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.
Yang YangSchool of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.
Guangze YangSchool of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.ORCID 0000-0002-6194-1918
Chun-Xia ZhaoSchool of Chemical Engineering, Faculty of Science, Engineering and Technology, The University of Adelaide, Adelaide, SA 5005 Australia.ORCID 0000-0002-3365-3759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide surfactants have been extensively investigated with various applications in detergents, foods, and pharmaceutics due to their biodegradability, biocompatibility, and customizable structures. Traditional peptide surfactants are often designed in a head-to-tail fashion mimicking chemical surfactants. Alternatively, a side-by-side design pattern based on heptad repeats offers an approach to designing peptide surfactants. However, minimalist peptide design using a single heptad for stabilizing interfaces remains largely unexplored. Here, we design four heptad surfactants (AM1.2, 6H, 6H7K, and HK) responsive to metal ions and compare their emulsification performance with a three-heptad peptide, AM1. Among them, the HK peptide generates emulsions exhibiting good stability over months. We further optimize factors such as buffering salts, ionic strength, and emulsion dilutions to uncover their impacts on emulsion properties. Our findings deepen the understanding of emulsion properties and provide practical insights for characterizing peptide-based emulsions, paving the way for their broader utilization in diverse applications.

Indexed as

ColloidsSoft materials

Identifiers

PMID39417162
PMCPMC11473402

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.