Evidence map›Paper›PMID 39417136›Full record

ArticlemedRxiv : the preprint server for health sciences2024

APOE4 carriers display loss of anticipatory cerebral vascular regulation over AD progression.

Jacqueline A Palmer, Carolyn S Kaufman, Alicen A Whitaker-Hilbig, Sandra A Billinger

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Jacqueline A PalmerDivision of Physical Therapy and Rehabilitation Science, University of Minnesota Medical School, , Minneapolis, MN, United States of America.ORCID 0000-0003-0021-4589
Carolyn S KaufmanDepartment of Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, KS, United States of America.
Alicen A Whitaker-HilbigDepartment of Physical Medicine and Rehabilitation, Medical College of Wisconsin, 123 Milwaukee Way, Milwaukee, WI, United States of America.
Sandra A BillingerDepartment of Neurology, University of Kansas Medical Center, Kansas City, KS, United States of America.

Funding

University of Kansas Alzheimer's Disease Research Center (KU ADRC)P30AG072973 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI JEFFREY Murray BURNS · 2021 to 2026
$25.3M
Training in Signature Transdisciplinary Cardiovascular SciencesT32HL134643 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Justin L Grobe, Jacquelyn P Kulinski · 2017 to 2026
$4.2M
Investigating cerebrovascular regulation during exercise as a factor influencing cortical resource engagement for balance control with agingR00AG075255 · NIA · UNIVERSITY OF MINNESOTA · PI Jacqueline A Palmer · 2024 to 2026
$742k
Investigating cerebrovascular regulation during exercise as a factor influencing cortical resource engagement for balance control with agingK99AG075255 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI PALMER, JACQUELINE A · 2022 to 2023
$234k
NHLBI NIH HHS T32 HL134643NIA NIH HHS K99 AG075255NIA NIH HHS P30 AG072973NIA NIH HHS R00 AG075255NICHD NIH HHS L30 HD099802
6 · The paper itself

Abstract

introductionMaintenance of cerebral blood flow during orthostasis is impaired with aging and associated with cognitive decline, but the effect of Apolipoprotein 4-allele (

methodsOlder adults (n=108) (

resultsCognitively-normal DISCUSSION:

Indexed as

Alzheimer’s diseaseApolipoprotein E4dynamic cerebral autoregulationmild cognitive impairmenttranscranial Doppler ultrasound

Identifiers

PMID39417136
PMCPMC11482999

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.