Evidence map›Paper›PMID 39417111›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Quantitative EEG Spectral Features Differentiate Genetic Epilepsies and Predict Neurologic Outcomes.

Peter D Galer, Jillian L McKee, Sarah M Ruggiero, Michael C Kaufman, Ian McSalley, Shiva Ganesan, William K S Ojemann, Alexander K Gonzalez, Quy Cao, Brian Litt and 2 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Peter D GalerDivision of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-6408-0906
Jillian L McKeeDivision of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0001-9724-0403
Sarah M RuggieroDivision of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-0834-0750
Michael C KaufmanDepartment of Biomedical and Health Informatics (DBHi), Children's Hospital of Philadelphia, Philadelphia, PA, 19146, USA.ORCID 0000-0003-2718-296X
Ian McSalleyDepartment of Biomedical and Health Informatics (DBHi), Children's Hospital of Philadelphia, Philadelphia, PA, 19146, USA.ORCID 0009-0007-9131-4847
Shiva GanesanDivision of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-2518-6505
William K S OjemannUniversity of Pennsylvania, Center for Neuroengineering and Therapeutics, Philadelphia, PA, 19104, USA.ORCID 0009-0007-5166-536X
Alexander K GonzalezDepartment of Biomedical and Health Informatics (DBHi), Children's Hospital of Philadelphia, Philadelphia, PA, 19146, USA.ORCID 0000-0002-4402-398X
Quy CaoDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-6204-1305
Brian LittUniversity of Pennsylvania, Center for Neuroengineering and Therapeutics, Philadelphia, PA, 19104, USA.ORCID 0000-0003-2732-6927
Ingo HelbigDivision of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0001-8486-0558
Erin C ConradUniversity of Pennsylvania, Center for Neuroengineering and Therapeutics, Philadelphia, PA, 19104, USA.ORCID 0000-0001-8910-1817

Funding

Ghost in the Machine: Melding Brain, Computer and BehaviorDP1NS122038 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI LITT, BRIAN · 2020 to 2024
$5.7M
A computational phenotyping approach to characterize neurogenetic disordersR01NS131512 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Ingo Helbig · 2023 to 2026
$2.8M
Subgroup delineation in genetic epilepsies and developmental brain disordersR01NS127830 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Ingo Helbig · 2023 to 2026
$2.8M
ClinGen Expert Curation Panel for the EpilepsiesU24NS120854 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Ingo Helbig, HEATHER C. MEFFORD · 2021 to 2026
$2.0M
Quantitative interictal networks to localize seizure generatorsK23NS121401 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Erin Conrad · 2022 to 2026
$1.2M
Joint analysis of genomic and electronic medical record data to assess outcomes and drug response in pediatric epilepsiesK02NS112600 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI HELBIG, INGO · 2020 to 2024
$963k
NINDS NIH HHS DP1 NS122038NINDS NIH HHS K02 NS112600NINDS NIH HHS K23 NS121401NINDS NIH HHS R01 NS127830NINDS NIH HHS R01 NS131512NINDS NIH HHS U24 NS120854
6 · The paper itself

Abstract

EEG plays an integral part in the diagnosis and management of children with genetic epilepsies. Nevertheless, how quantitative EEG features differ between genetic epilepsies and neurological outcomes remains largely unknown. Here, we aimed to identify quantitative EEG biomarkers in children with epilepsy and a genetic diagnosis in

Identifiers

PMID39417111
PMCPMC11482972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.