Evidence map›Paper›PMID 39417001›Full record

ReviewInternational journal of cardiology. Cardiovascular risk and prevention2024

Assessment of cardiovascular risk in patients with ANCA-associated vasculitis: A systematic review and meta-analysis.

Aman Goyal, Haleema Qayyum Abbasi, Yusra Mashkoor, Abdul Moiz Khan, Samia Aziz Sulaiman, Mohamed Daoud, Kamna Bansal

Abstract readReview
In one paragraph

Review in International journal of cardiology. Cardiovascular risk and prevention, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. The Wound-Heart Axis: Can Chronic Wounds Contribute to Cardiac Dysfunction?International journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aman GoyalDepartment of Internal Medicine, Seth GS Medical College and KEM Hospital, Mumbai, India.
Haleema Qayyum AbbasiDepartment of Internal Medicine, Ayub Medical College, Abbottabad, Pakistan.
Yusra MashkoorDepartment of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.
Abdul Moiz KhanDepartment of Internal Medicine, Ayub Medical College, Abbottabad, Pakistan.
Samia Aziz SulaimanSchool of Medicine, University of Jordan, Amman, Jordan.
Mohamed DaoudDepartment of Internal Medicine, Bogomolets National Medical University, Kyiv, Ukraine.
Kamna BansalBaylor College of Medicine, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although many chronic inflammatory conditions are linked to elevated cardiovascular risk, the specific extent of this risk in ANCA-associated vasculitis (AAV) remains elusive, largely due to the disease's rarity. Our study sought to clarify the cardiovascular risks and mortality linked to AAV. Methods: A systematic literature review was conducted across multiple databases from their inception until April 2024 to identify studies comparing cardiovascular outcomes in patients with and without AAV. R Studio's meta package was used to pool risk ratios under the random-effects model, and statistical significance was set at p < 0.05. Results: Nine observational studies involving 45024 individuals were included in this analysis. Patients with AAV exhibited a significantly elevated risk of stroke (RR = 1.43, 95 % CI: 1.12-1.83, I2 = 62 %, p = 0.0048), myocardial infarction (RR = 1.49, 95 % CI: 1.25-1.79, Conclusion: This meta-analysis underscores a notable increase in adverse cardiovascular events among patients with AAV, underscoring the need for comprehensive cardiovascular care and diligent monitoring in this patient cohort.

Indexed as

ANCA-Associated vasculitisCardiovascular disease-related mortalityCardiovascular riskMeta-analysis

Identifiers

PMID39417001
PMCPMC11481614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.