Evidence map›Paper›PMID 39416970›Full record

ArticleACS pharmacology & translational science2024

Inhalable Advanced Co-Spray Dried Microparticles/Nanoparticles of a Novel RhoA/Rho Kinase Inhibitor with Lung Surfactant Biomimetic Phospholipids for Targeted Lung Delivery.

Victor H Ruiz, David Encinas-Basurto, Neftali Ortega-Alarcon, Basanth Babu Eedara, Jeffrey R Fineman, Stephen M Black, Heidi M Mansour

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victor H RuizThe University of Arizona College of Pharmacy, Skaggs Pharmaceutical Sciences Center, Tucson, Arizona85721, United States.
David Encinas-BasurtoThe University of Arizona College of Pharmacy, Skaggs Pharmaceutical Sciences Center, Tucson, Arizona85721, United States.
Neftali Ortega-AlarconThe University of Arizona College of Pharmacy, Skaggs Pharmaceutical Sciences Center, Tucson, Arizona85721, United States.
Basanth Babu EedaraThe University of Arizona College of Pharmacy, Skaggs Pharmaceutical Sciences Center, Tucson, Arizona85721, United States.
Jeffrey R FinemanDepartment of Pediatrics, University of California San Francisco School of Medicine, San Francisco, California 94143, United States.
Stephen M BlackCenter for Translational Science, Florida International University, Port St. Lucie, Florida 34987, United States.
Heidi M MansourThe University of Arizona College of Pharmacy, Skaggs Pharmaceutical Sciences Center, Tucson, Arizona85721, United States.ORCID https://orcid.org/0000-0003-3993-9210

Funding

TGF-ß-SOX18-Collagen metabolism in pulmonary vascular disease associated with CHDP01HL146369 · NHLBI · UNIVERSITY OF ARIZONA · PI Stephen M Black · 2020 to 2026
$18.7M
Perinatal NO signaling in congenital heart diseaseR01HL137282 · NHLBI · UNIVERSITY OF ARIZONA · PI BLACK, STEPHEN M, FINEMAN, JEFFREY R · 2017 to 2020
$2.7M
NHLBI NIH HHS P01 HL146369NHLBI NIH HHS R01 HL137282
6 · The paper itself

Abstract

Co-spray dried inhalable powder formulations of fasudil monohydrochloride salt (FMCS) and inhalable lung surfactant-based nanocarriers composed of synthetic phospholipids, zwitterionic DPPC (1,2-palmitoyl-

Identifiers

PMID39416970
PMCPMC11475283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.