Evidence map›Paper›PMID 39416773›Full record

ArticleFrontiers in immunology2024

IL-33-primed human mast cells drive IL-9 production by CD4

Louise Battut, Edouard Leveque, Salvatore Valitutti, Nicolas Cenac, Gilles Dietrich, Eric Espinosa

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Paradoxical Expression of Ionotropic Glutamate Receptors in Leucocytes.Clinical reviews in allergy & immunology · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Louise Battut *Université Toulouse III - Paul Sabatier, FSI, Toulouse, France.
Edouard Leveque *Université Toulouse III - Paul Sabatier, FSI, Toulouse, France.
Salvatore ValituttiUniversité Toulouse III - Paul Sabatier, FSI, Toulouse, France.
Nicolas CenacUniversité Toulouse III - Paul Sabatier, FSI, Toulouse, France.
Gilles DietrichUniversité Toulouse III - Paul Sabatier, FSI, Toulouse, France.
Eric EspinosaUniversité Toulouse III - Paul Sabatier, FSI, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-33 (IL-33) is an alarmin released by epithelial cells in response to tissue damage. It activates resident immune sentinel cells, which then produce signals commonly associated with type 2 immune responses, particularly affecting infiltrating antigen-specific T cells. Given that mast cells (MCs) are a primary target of IL-33 and can shape T helper (Th) cell responses, we investigated the effect of IL-33 priming on the ability of MCs to influence Th cell cytokine production. To examine the Th cell/MC interaction, we developed human primary MC/memory CD4

Indexed as

CD4-Positive T-LymphocytesInterleukin-33Interleukin-9Mast CellsOX40 LigandCells, CulturedCoculture TechniquesHumansInterleukin-13Lymphocyte ActivationIL33 protein, humanIL9 protein, humanInterleukin-13Interleukin-33Interleukin-9OX40 LigandTNFSF4 protein, humanIL-33IL-9mast cellOX40LTh cell

Identifiers

PMID39416773
PMCPMC11479898

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.