Evidence map›Paper›PMID 39416767›Full record

ArticleClinical & translational immunology2024

Naturally acquired adaptive immunity to

Giuseppe Ercoli, Hugh Selway-Clarke, Dena Truijen, Milda Folkmanaite, Tate Oulton, Caitlin Norris-Grey, Rie Nakajima, Philip Felgner, Brendan W Wren, Kevin Tetteh and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical & translational immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giuseppe ErcoliUCL Respiratory, Division of Medicine, Rayne Institute University College London London UK.ORCID https://orcid.org/0000-0001-7326-1680
Hugh Selway-ClarkeUCL Respiratory, Division of Medicine, Rayne Institute University College London London UK.
Dena TruijenUCL Respiratory, Division of Medicine, Rayne Institute University College London London UK.
Milda FolkmanaiteUCL Respiratory, Division of Medicine, Rayne Institute University College London London UK.
Tate OultonDepartment of Infection Biology London School of Hygiene & Tropical Medicine London UK.
Caitlin Norris-GreyCentre for Rheumatology and Bloomsbury Rheumatology Unit, Division of Medicine University College London London UK.
Rie NakajimaVaccine Research and Development Center, Department of Physiology and Biophysics University of California Irvine Irvine CA USA.
Philip FelgnerVaccine Research and Development Center, Department of Physiology and Biophysics University of California Irvine Irvine CA USA.
Brendan W WrenDepartment of Infection Biology London School of Hygiene & Tropical Medicine London UK.
Kevin TettehDepartment of Infection Biology London School of Hygiene & Tropical Medicine London UK.
Nicholas J CroucherMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology School of Public Health, Imperial College London London UK.
Maria LeandroCentre for Rheumatology and Bloomsbury Rheumatology Unit, Division of Medicine University College London London UK.
Geraldine CambridgeCentre for Rheumatology and Bloomsbury Rheumatology Unit, Division of Medicine University College London London UK.
Jeremy S BrownUCL Respiratory, Division of Medicine, Rayne Institute University College London London UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Objectives: Patients with rheumatoid arthritis (RA) have an increased susceptibility to infections, including those caused by Methods: IgG responses to Results: Compared to a well-characterised disease control group of ME/CFS patients, RA patients had reduced antibody responses to multiple Conclusion: These data show RA is associated with major disruption of naturally acquired adaptive immunity to

Indexed as

anti‐protein antibodyB‐cell depletionimmunosuppression treatmentsrheumatoid arthritisStreptococcus pneumoniae

Identifiers

PMID39416767
PMCPMC11480415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.