Evidence map›Paper›PMID 39416551›Full record

ReviewCureus2024

A Review and Bibliometric Analysis of Studies on Advances in Peripheral Nerve Regeneration.

Billy McBenedict, Wilhelmina N Hauwanga, Gabriel Escudeiro, Dulci Petrus, Barakat B Onabanjo, Chukwuwike Johnny, Mohamed Omer, Amoolya R Amaravadhi, Asaju Felix, Ngoc B Dang and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Billy McBenedictNeurosurgery, Fluminense Federal University, Niterói, BRA.
Wilhelmina N HauwangaCardiology, Faculty of Medicine, Federal University of the State of Rio de Janeiro, Rio de Janeiro, BRA.
Gabriel EscudeiroNeurosurgery, Fluminense Federal University, Niterói, BRA.
Dulci PetrusFamily Medicine, Directorate of Special Programs, Ministry of Health and Social Services, Windhoek, NAM.
Barakat B OnabanjoResearch and Development, Montefiore Medical Center, Wakefield Campus, New York City, USA.
Chukwuwike JohnnyFamily Medicine, Life Point Medical Centre, Abuja, NGA.
Mohamed OmerInternal Medicine, Sulaiman Al Rajhi University, Ar Rass, SAU.
Amoolya R AmaravadhiInternal Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad, IND.
Asaju FelixGeneral Practice, Dorset County Hospital, Dorchester, GBR.
Ngoc B DangNursing, College of Health Sciences, VinUniversity, Hanoi, VNM.
Lorena AdolphssonNeurosurgery, Fluminense Federal University, Niteroi, BRA.
Bruno Lima PessôaNeurosurgery, Fluminense Federal University, Niterói, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve injuries (PNIs) pose significant clinical challenges due to their complex healing processes and the often incomplete functional recovery. This review and bibliometric analysis aimed to provide a comprehensive overview of advancements in peripheral nerve regeneration research, focusing on trends, influential studies, and emerging areas. By analyzing 2921 publications from the Web of Science Core Collection, key themes such as nerve regeneration, repair, and the critical role of Schwann cells were identified. The study highlights a notable increase in research output since the early 2000s, with China and the United States leading in publication volume and citations. The analysis also underscores the importance of collaborative networks, which are driving innovation in this field. Despite significant progress, the challenge of achieving complete functional recovery from PNIs persists, emphasizing the need for continued research into novel therapeutic strategies. This review synthesizes current knowledge on the mechanisms of nerve regeneration, including the roles of cellular and molecular processes, neurotrophic factors, and emerging therapeutic approaches such as gene therapy and stem cell applications. Additionally, the study revealed the use of nanotechnology, biomaterials, and advanced imaging techniques, which hold promise for improving the outcomes of nerve repair. This bibliometric analysis not only maps the landscape of peripheral nerve regeneration research but also identifies opportunities for future investigation. This study has some limitations, including reliance on the Web of Science Core Collection, which may exclude relevant research from other databases. The analysis is predominantly English-based, potentially overlooking significant non-English studies. Citation trends might be influenced by shifting research priorities and accessibility issues, affecting the visibility of older work. Additionally, geographical disparities and limited collaboration networks may restrict the global applicability and knowledge exchange in this field.

Indexed as

bibliometric analysisfunctional recoveryperipheral nerve regenerationresearch trendsschwann cells

Identifiers

PMID39416551
PMCPMC11481412

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.