ReviewReproductive medicine and biology
Molecular mechanisms of mammalian sperm capacitation, and its regulation by sodium-dependent secondary active transporters.
Review in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Niemann-Pick type C2-mediated cholesterol sequestration induces capacitation-like sperm remodeling during reproductive tract transit in the blue swimming crab (Portunus pelagicus).Veterinary world · 2026Article
- Reactive Oxygen Species-Induced Damage in Cryopreserved Bovine Sperm: Mitigation Strategies.Veterinary medicine and science · 2026Review
- The systems that transport ions and their impact on sperm function and male fertility.Function (Oxford, England) · 2026Review
- The Sperm Acrosomal Reaction Depends on the Function of Both Na,K-ATPase α1 and α4 Isoforms.International journal of molecular sciences · 2026Article
- Review
- Sperm subpopulations differing in mitochondrial abundance show divergent nuclear allele frequencies.PloS one · 2026Article
- Role of the CaCells · 2025Article
- Developmental switch in immunolocalization of phosphodiesterase 7A protein in testicular cells of mice, rats, and camels.Open veterinary journal · 2025Article
- Functions of ectodysplasin A2 receptor (EDA2R) in inducing capacitation of sperm in mice.In vitro cellular & developmental biology. Animal · 2025Article
- Redox signaling regulation in human spermatozoa: a primary role of peroxiredoxins.Asian journal of andrology · 2025Review
- Molecular mechanisms of mammalian sperm capacitation, and its regulation by sodium-dependent secondary active transporters.Reproductive medicine and biologyReview
- Activation of motility and chemotaxis in the spermatozoa.Reproductive medicine and biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mammalian spermatozoa have to be "capacitated" to be fertilization-competent. Capacitation is a collective term for the physiological and biochemical changes in spermatozoa that occur within the female body. However, the regulatory mechanisms underlying capacitation have not been fully elucidated. Methods: Previously published papers on capacitation, especially from the perspective of ions/channels/transporters, were extracted and summarized. Results: Capacitation can be divided into two processes: earlier events (membrane potential hyperpolarization, intracellular pH rise, intracellular Ca Conclusion: The hypotheses are (1) hyperpolarizing Na
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.