Evidence map›Paper›PMID 39416254›Full record

ArticleJournal of arrhythmia2024

Efficacy and safety of pulsed-field versus conventional thermal ablation for atrial fibrillation: A systematic review and meta-analysis.

Ahmed Mazen Amin, Abubakar Nazir, Mohamed T Abuelazm, Ahmed A Ibrahim, Hossam Elbenawi, Aya Aboutaleb, Mohamed Ellabban, Moumen Arnaout, Mustafa Turkmani, Basel Abdelazeem and 1 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Active Compression During External Cardioversion of Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2025
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  15. Unintended lesion formation and conduction block in the posterior left atrium during pulmonary vein isolation using a pentaspline pulsed field ablation catheter.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
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  20. Pulsed-field ablation vs. thermal ablation for paroxysmal atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmed Mazen AminFaculty of Medicine Mansoura University Mansoura Egypt.
Abubakar NazirFaculty of Medicine King Edward Medical University Lahore Pakistan.
Mohamed T AbuelazmFaculty of Medicine Tanta University Tanta Egypt.
Ahmed A IbrahimFaculty of Medicine Menoufia University Menoufia Egypt.
Hossam ElbenawiDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota USA.
Aya AboutalebFaculty of Medicine Zagazig University Zagazig Egypt.
Mohamed EllabbanFaculty of Medicine Al-Azhar University Cairo Egypt.
Moumen ArnaoutFaculty of Medicine Aleppo University Aleppo Syria.
Mustafa TurkmaniFaculty of Medicine Michigan State University East Lansing Michigan USA.ORCID https://orcid.org/0009-0001-4261-0638
Basel AbdelazeemDepartment of Cardiology West Virginia University West Virginia USA.
Annabelle S VolgmanDivision of Cardiology Rush University Medical Center Chicago Illinois USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulsed-field ablation (PFA) has emerged as an innovative alternative to radiofrequency (RF) and cryoablation because it selectively targets myocardial tissue. Thus, we aim to estimate the efficacy and safety of PFA versus thermal ablation for atrial fibrillation (AF) ablation. Methods: A systematic review and meta-analysis were retrieved from PubMed, WOS, SCOPUS, EMBASE, and CENTRAL through September 2023. We used RevMan V. 5.4 to pool dichotomous data using risk ratio (RR) and continuous data using mean difference (MD) with a 95% confidence interval (CI). PROSPERO ID: CRD42023480321. Results: We included 17 studies with a total of 2255 patients. PFA was significantly associated with a decreased incidence of AF recurrence (RR: 0.66 with 95% CI [0.51, 0.87], Conclusion: PFA was significantly associated with decreased AF recurrence, total procedure time, heart rate change, phrenic nerve palsy, esophageal lesion, and increased incidence of pericardial tamponade compared with thermal ablation.

Indexed as

ablationatrial fibrillationpulsed‐field

Identifiers

PMID39416254
PMCPMC11474578

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.