Evidence map›Paper›PMID 39416191›Full record

ArticlebioRxiv : the preprint server for biology2024

Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains.

Zachary Hemminger, Gabriela Sanchez-Tam, Haley De Ocampo, Aihui Wang, Thomas Underwood, Fangming Xie, Qiuying Zhao, Dongyuan Song, Jingyi Jessica Li, Hongwei Dong and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zachary HemmingerBiocartography Inc.
Gabriela Sanchez-TamDepartment of Chemistry and Biochemistry, UCLA.
Haley De OcampoDepartment of Chemistry and Biochemistry, UCLA.
Aihui WangDepartment of Chemistry and Biochemistry, UCLA.
Thomas UnderwoodDepartment of Chemistry and Biochemistry, UCLA.
Fangming XieDepartment of Chemical Biology, David Geffen School of Medicine at UCLA.
Qiuying ZhaoDepartment of Neurobiology, David Geffen School of Medicine at UCLA.
Dongyuan SongIndependent Program in Bioinformatics, UCLA.
Jingyi Jessica LiDepartment of Statistics and Data Science, UCLA.ORCID 0000-0002-9288-5648
Hongwei DongDepartment of Neurobiology, David Geffen School of Medicine at UCLA.ORCID 0000-0001-9972-3177
Roy WollmanDepartment of Chemistry and Biochemistry, UCLA.ORCID 0000-0003-3865-2605

Funding

Spatiotemporal Molecular Substrates of TBI at Single Cell ResolutionR01NS117148 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GOMEZ-PINILLA, FERNANDO, WOLLMAN, ROY · 2020 to 2024
$2.8M
Whole organ transcriptome reconstruction by dimensionality reduced fluorescent in situ hybridizationR01HG012925 · NHGRI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jingyi Jessica Li, Roy Wollman · 2024 to 2026
$1.9M
NHGRI NIH HHS R01 HG012925NINDS NIH HHS R01 NS117148
6 · The paper itself

Abstract

Genetic variation can alter brain structure and, consequently, function. Comparative statistical analysis of mouse brains across genetic backgrounds requires spatial, single-cell, atlas-scale data, in replicates-a challenge for current technologies. We introduce

Identifiers

PMID39416191
PMCPMC11483037

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.