Evidence map›Paper›PMID 39416164›Full record

ArticlebioRxiv : the preprint server for biology2024

Activation and modulation of the host response to DNA damage by an integrative and conjugative element.

Saria McKeithen-Mead, Mary E Anderson, Alam García-Heredia, Alan D Grossman

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Saria McKeithen-MeadDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.
Mary E AndersonDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.
Alam García-HerediaDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.
Alan D GrossmanDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139 USA.

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
QUORUM SENSING AND GENE EXPRESSION IN BACILLUS SUBTILISR01GM050895 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GROSSMAN, ALAN D · 1994 to 2017
$5.6M
Mechanisms and regulation of replication, the cell cycle, gene expression, and horizontal gene transfer in prokaryotes, focusing on Bacillus subtilisR35GM122538 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GROSSMAN, ALAN D · 2017 to 2021
$3.2M
Mechanisms and regulation of replication, the cell cycle, gene expression, and horizontal gene transfer in prokaryotes, focusing on Bacillus subtilis.R35GM148343 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ALAN D GROSSMAN · 2023 to 2026
$3.1M
NIGMS NIH HHS R01 GM050895NIGMS NIH HHS R35 GM122538NIGMS NIH HHS R35 GM148343NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

Mobile genetic elements help drive horizontal gene transfer and bacterial evolution. Conjugative elements and temperate bacteriophages can be stably maintained in host cells. They can alter host physiology and regulatory responses and typically carry genes that are beneficial to their hosts. We found that ICE

Indexed as

Bacillus subtilisconjugationDNA damagehorizontal gene transferICEBs1integrative and conjugative elementsmobile genetic elementsRecASOS response

Identifiers

PMID39416164
PMCPMC11482772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.