Evidence map›Paper›PMID 39416119›Full record

ArticlebioRxiv : the preprint server for biology2025

Real-time genomic characterization of pediatric acute leukemia using adaptive sampling.

Julie Geyer, Kofi B Opoku, John Lin, Lori Ramkissoon, Charles Mullighan, Nickhill Bhakta, Thomas B Alexander, Jeremy R Wang

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Julie GeyerDepartment of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kofi B OpokuDepartment of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
John LinDepartment of Genetics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Lori RamkissoonDepartment of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Charles MullighanDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Nickhill BhaktaDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.
Thomas B AlexanderDepartment of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-0484-1574
Jeremy R WangDepartment of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-0673-9418

Funding

Characterization of Diverse Pediatric Cancers in LMIC Using Low-Cost Nanopore SequencingR01CA293366 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Thomas Blick Alexander, Jeremy R Wang · 2024 to 2026
$3.0M
Predoctoral Training Program in Bioinformatics and Computational BiologyT32GM135123 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Michael Isaiah Love, William Valdar · 2021 to 2026
$1.7M
Novel Sequencing Based Diagnostics for Leukemia in Low Resource SettingsR21CA259926 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALEXANDER, THOMAS BLICK, WANG, JEREMY R · 2022 to 2023
$400k
NCI NIH HHS R01 CA293366NCI NIH HHS R21 CA259926NIGMS NIH HHS T32 GM135123
6 · The paper itself

Abstract

Effective treatment of pediatric acute leukemia is dependent on accurate genomic classification, typically derived from a combination of multiple time-consuming and costly techniques such as flow cytometry, fluorescence

Identifiers

PMID39416119
PMCPMC11483067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.