Evidence map›Paper›PMID 39415914›Full record

ArticleEJHaem2024

Single-centre experience of implementing physiotherapist-led prehabilitation for chimeric antigen receptor T cell therapy.

Orla McCourt, Paul Maciocia, Claire Roddie, Angela Hwang, Leigh Wood, Aikaterini Panopoulou, Deborah Ann Springell, Maise Al Bakir, Maeve O'Reilly

Abstract read
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Orla McCourtDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0001-7572-2540
Paul MaciociaDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0002-9757-8073
Claire RoddieDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0002-4901-5858
Angela HwangDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0009-0004-4938-0910
Leigh WoodDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.
Aikaterini PanopoulouDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0003-3254-3379
Deborah Ann SpringellDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0001-7166-5200
Maise Al BakirDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0002-0846-8332
Maeve O'ReillyDepartment of Haematology University College London Hospitals NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0002-2702-397X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This report outlines the evaluation of physiotherapist-led prehabilitation/rehabilitation for recipients of chimeric antigen receptor T (CAR-T) cell therapy. Methods: A hybrid approach was used, incorporating in-person assessment of quality of life and functional capacity (6-min walk test and timed sit-to-stand test), and a personalised home exercise programme with remotely delivered physiotherapist support pre/post-admission. Results: Functional deficits were prevalent at referral for CAR-T. Prehabilitation and rehabilitation were highly acceptable to patients, and improvements in functional capacity were documented pre-admission. Conclusion: This data highlights the importance of pre-CAR-T functional assessment and prehabilitation to optimise preparation and recovery.

Indexed as

chimeric antigen receptor T‐cell therapyexercisephysiotherapyrehabilitation

Identifiers

PMID39415914
PMCPMC11481005

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.