Evidence map›Paper›PMID 39415899›Full record

ArticleEJHaem2024

The genomic landscape of transformed splenic diffuse red pulp small B-cell lymphoma.

Marta Grau, Melina Pol, Anna Montaner, Pablo Mozas, Ferran Nadeu, Ian Márquez-López, Jose Ramon Álamo, Alba Navarro, Daniel Martinez, Gerard Frigola and 12 more

Abstract read
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Marta GrauFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Melina PolFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Anna MontanerFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Pablo MozasFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID https://orcid.org/0000-0001-9528-4971
Ferran NadeuFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID https://orcid.org/0000-0003-2910-9440
Ian Márquez-LópezFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID https://orcid.org/0000-0003-4416-5184
Jose Ramon ÁlamoHematopathology Section, Pathology Department Hospital Clínic de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0001-8579-082X
Alba NavarroFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Daniel MartinezHematopathology Section, Pathology Department Hospital Clínic de Barcelona Barcelona Spain.
Gerard FrigolaHematopathology Section, Pathology Department Hospital Clínic de Barcelona Barcelona Spain.
Olga BalaguéFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Mónica Lopez-GuerraFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Dolors ColomerFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Silvia Ruiz-GaspàFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Melika BashiriFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Juan CorreaHematology Department Hospital Clínic de Barcelona Barcelona Spain.
Eva GinéFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Armando López-GuillermoFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Elias CampoFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Cristina LópezFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.
Estella MatutesHematology Department Hospital Clínic de Barcelona Barcelona Spain.ORCID https://orcid.org/0000-0001-6745-7046
Sílvia BeàFundació Recerca Clínic Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.ORCID https://orcid.org/0000-0001-7192-2385

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic landscape underlying the transformation of splenic diffuse red pulp small B-cell lymphoma (SDRPL) is not well understood. The present study aimed to unravel the genomic alterations involved in the progression and transformation of SDRPL. We performed genetic studies on both SDRPL and subsequent or synchronous diffuse large B cell lymphoma (DLBCL) samples in three SDRPL patients who eventually developed DLBCL. Our findings revealed that SDRPL cases progressing to DLBCL acquired genomic alterations in genes related to the cell cycle (

Indexed as

B‐cell developementcell cycleclonal relationshipgenetic alterationshistologic transformationsplenic diffuse red pulp small B‐cell lymphoma

Identifiers

PMID39415899
PMCPMC11474344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.