Evidence map›Paper›PMID 39415628›Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2024

HIV Pre-Exposure Prophylaxis (PrEP) Users' Experiences of PrEP Access, Sexual Behaviour, and Well-Being During the COVID-19 Pandemic: A Welsh Qualitative Study.

Zahraa Khammas, David Gillespie, Adam Dale Newman Williams, Jane Nicholls, Fiona Wood

Abstract read
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zahraa KhammasCardiff University School of Medicine, Cardiff University, Cardiff, UK.ORCID 0009-0009-3672-9956
David GillespieCentre for Trials Research, Cardiff University, Cardiff.ORCID 0000-0002-6934-2928
Adam Dale Newman WilliamsCentre for Trials Research, Cardiff University, Cardiff.ORCID 0000-0002-4825-8997
Jane NichollsCentre for Trials Research, Cardiff University, Cardiff.ORCID 0000-0003-0933-8377
Fiona WoodDivision of Population Medicine, PRIME Centre Wales, Cardiff University, Cardiff, UK.ORCID 0000-0001-7397-4074

Funding

The Centre for Trials Research is funded by Health & Care Research Wales and Cancer Research UK. PRIME Centre Wales is funded by Health & Care Research Wales. DO-PrEP was funded by Health and Care Research Wales (Award Number HF-17-1411). UPrEP was funded by the Knowledge Economy Skills Scholarship (KESS2).
6 · The paper itself

Abstract

backgroundHIV Pre-Exposure Prophylaxis (PrEP) has been available in Wales since 2017. The coronavirus disease (COVID-19) pandemic impacted UK sexual health services, leading to a reduction in service provision. There is a lack of research on the experiences of PrEP users during this time.

objectiveWe aimed to explore the experiences of PrEP users in Wales following the introduction of COVID-19 pandemic measures.

methodsWe conducted a secondary data analysis of two prior interview studies (DO-PrEP and UPrEP). Data collection was undertaken between May 2020 and February 2021 using remote interviewing. Semi-structured interviews were conducted. Participants were ≥18 years of age, residents of Wales, current or previous PrEP users, and men who have sex with men (MSM). Reflexive thematic analysis was conducted.

resultsA total of 32 interviews were included in the analysis. Themes include the following: (1) PrEP use during COVID-19, (2) sexual behaviour and relationship changes following COVID-19 restrictions, (3) NHS service provision during the COVID-19 pandemic, and (4) wider contextual effects of the pandemic. Participants reported a change in PrEP use (pausing or switching to event-based PrEP). Participants reported reduced access to clinics and appointments. Support for changing to event-based PrEP was varied. Social isolation resulted in varied responses to lockdown rules, especially in later lockdowns.

conclusionThis study provides patient perspectives on the challenges the COVID-19 pandemic posed to PrEP use and access. It offers insights into the broader support needs around PrEP use when an individual's circumstances change. Flexible models of PrEP provision, which can be adapted to the patient's needs, will be essential as PrEP delivery extends into the wider community. PATIENT AND PUBLIC CONTRIBUTION: Both the DO-PrEP and UPrEP studies received input from various stakeholders in the design of the topic guides for the study; these included public lay members, PrEP users, PrEP providers, and individuals involved with HIV advocacy and policy.

Indexed as

COVID-19HIV InfectionsPre-Exposure ProphylaxisQualitative ResearchSexual BehaviorAdultFemaleHealth Services AccessibilityHomosexuality, MaleHumansInterviews as TopicMaleMiddle AgedPandemicsSARS-CoV-2WalesCOVID‐19HIVPrEPqualitative researchsexual behaviour

Identifiers

PMID39415628
PMCPMC11483589

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.