Evidence map›Paper›PMID 39415293›Full record

Observational studyAddiction science & clinical practice2024

Are the self-stigma and perceived stigma of patients treated with methadone or buprenorphine still a problem fifty years after the marketing authorization for opioid agonist treatment? The observational STIGMA study.

Mélanie Pinhal, Benoit Schreck, Juliette Leboucher, STIGMA-group, Caroline Victorri-Vigneau, Edouard-Jules Laforgue, Marie Grall-Bronnec

Abstract readObservational Study
In one paragraph

Observational study in Addiction science & clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The Effect of Federal Policy Changes on Buprenorphine Prescribing in Massachusetts.Journal of the American College of Emergency Physicians open · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mélanie PinhalAddictive Medicine and Psychiatry Department, Nantes Université, CHU Nantes, 44000, Nantes, France.
Benoit SchreckAddictive Medicine and Psychiatry Department, Nantes Université, CHU Nantes, 44000, Nantes, France.
Juliette LeboucherAddictive Medicine and Psychiatry Department, Nantes Université, CHU Nantes, 44000, Nantes, France.
STIGMA-group
Caroline Victorri-VigneauNantes Université, Univ Tours, CHU Nantes, CHU Tours, INSERM, MethodS in Patients Centered Outcomes and HEalth ResEarch, SPHERE, 44000, Nantes, France.
Edouard-Jules LaforgueAddictive Medicine and Psychiatry Department, Nantes Université, CHU Nantes, 44000, Nantes, France.
Marie Grall-BronnecAddictive Medicine and Psychiatry Department, Nantes Université, CHU Nantes, 44000, Nantes, France. marie.bronnec@chu-nantes.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the context of the opioid overdose crisis, understanding the barriers to seeking, attaining and remaining in treatment for patients with opioid use disorder (OUD) is a public health issue. To date, very few studies have assessed the "self-stigma" (i.e., the internalization of negative societal attitudes and stereotypes about oneself, leading to self-judgment) and "perceived stigma" (i.e., the belief that others hold negative attitudes towards oneself due to a particular condition) experienced by patients with OUD receiving opioid agonist treatment (OAT), and none have done so in France. Our study aimed to quantify self-stigma, explore some aspects of perceived stigma, determine the factors associated with greater self-stigma and examine whether the level of self-stigma was related to a delay in seeking care.

methodsThe STIGMA study was a monocentric, cross-sectional study. The data were collected in a French hospital addiction medicine department. Participants were outpatients with current or past OUD who were still receiving or had received OAT. A questionnaire assessing sociodemographics; OUD characteristics; perceived stigma; and quantification of self-stigma by the Self-Stigma Scale-Short, was administered.

resultsA total of 73 questionnaires were included in the analysis. Nearly two-thirds of the patients had a "moderate to high" level of self-stigma. These patients were significantly younger at OUD onset and were significantly more likely to have at least one dependent child than patients reporting a "very low to low" level of self-stigma. Nearly half of the participants experienced perceived stigma from a healthcare professional regarding their OUD or OAT, and nearly one-third of the participants were refused care from a healthcare professional because of their OUD or OAT. Moreover, a quarter of the sample reported delaying care due to fear of being stigmatized. We did not find a relationship between self-stigma levels and a delay in seeking care.

conclusionsOur study highlights the need to detect stigma and to improve training in addiction medicine.

Indexed as

BuprenorphineMethadoneOpiate Substitution TreatmentOpioid-Related DisordersSocial StigmaAdultAnalgesics, OpioidCross-Sectional StudiesFemaleFranceHumansMaleMiddle AgedPatient Acceptance of Health CareSelf ConceptAnalgesics, OpioidBuprenorphineMethadoneBarrier to treatmentOpioid agonist treatmentOpioid use disorderPerceived stigmaSelf-stigma

Identifiers

PMID39415293
PMCPMC11481267

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.