Evidence map›Paper›PMID 39415228›Full record

ArticleCardio-oncology (London, England)2024

Cardiac events among a cohort of 17,389 patients receiving cancer chemotherapy: short and long term implications.

Saifei Liu, John D Horowitz, Bogda Koczwara, Aaron L Sverdlov, Natalie Packer, Robyn A Clark

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardio-oncology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The gut-heart axis in cardio-oncology.Cardiovascular research · 2026
    Review
  2. Article
  3. Risk factors associated with cardiovascular hospital admissions and all-cause mortality in cancer patients treated with immune checkpoint inhibitors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saifei LiuCardiovascular Pathophysiology & Therapeutics Group, The Basil Hetzel Institute for Translational Research, University of Adelaide, Adelaide, SA, Australia. saifei.liu@adelaide.edu.au.
John D HorowitzCardiovascular Pathophysiology & Therapeutics Group, The Basil Hetzel Institute for Translational Research, University of Adelaide, Adelaide, SA, Australia.
Bogda KoczwaraCollege of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.
Aaron L SverdlovNewcastle Centre of Excellence in Cardio-Oncology: Calvary Mater Newcastle, Hunter Medical Research Institute, University of Newcastle, Newcastle, NSW, Australia.
Natalie PackerSouthern Adelaide Local Health Network, Adelaide, SA, Australia.
Robyn A ClarkCaring Futures Institute, Flinders University, Southern Adelaide Local Health Network, Adelaide, SA, Australia.

Funding

National Heart Foundation of Australia Future Leader Fellowship 100847National Heart Foundation of Australia Future Leader Fellowship 106025
6 · The paper itself

Abstract

backgroundThe association between cardiovascular disease and carcinogenesis is bidirectional and well-established. Furthermore, cancer treatment improves overall patient survival, potentially at the cost of incremental and fatal cardiovascular disease (CVD).

aimTo evaluate (a) In a real-world cohort, the proportion of patients offered cancer chemotherapy who have antecedent CVD (CVD

methodsRetrospective analysis was performed in deidentified linked health data sets. Correlates of mortality were evaluated by Cox proportional hazards evaluation. Relative and absolute time-variability of CVD as a primary cause of death were determined.

resultsOf the total 17,389 patients, there were 2,159 with CVD

conclusionsApproximately 50% of patients assigned to cancer chemotherapy developed CVD

Indexed as

CardiotoxicityChemotherapyClinical outcomesCVDLinked-data

Identifiers

PMID39415228
PMCPMC11481733

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.