Evidence map›Paper›PMID 39415226›Full record

ArticleJournal of nanobiotechnology2024

Photothermal Fe

Yue Li, Jia Chen, Qi Xia, Jing Shang, Yujie He, Zhi Li, Yingying Chen, Feng Gao, Xi Yu, Zeting Yuan and 1 more

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Transrectal Biplane Ultrasound Features and Clinical Characteristics Associated With T3-T4 Staging of Rectal Cancer: A Retrospective Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Spatiotemporal cancer controlNanomedicine (London, England) · 2026
    Review
  7. Size-Dependent Immunomodulatory Effects of FeMolecules (Basel, Switzerland) · 2026
    Article
  8. Iron-Based Nanoparticles as Delivery Tools.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Recent advances in novel targeting mechanisms for colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yue Li *Interventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Jia Chen *Interventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Qi XiaInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Jing ShangInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Yujie HeInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Zhi LiInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Yingying ChenInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China.
Feng GaoDepartment of Pharmaceutics, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
Xi YuInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China. 495003741@qq.com.
Zeting YuanInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China. yuan340202@163.com.
Peihao YinInterventional Cancer Institute of Chinese Integrative Medicine & Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200062, China. yinpeihao@shutcm.edu.cn.

Funding

Clinical Specialized Discipline of Health System of Putuo District in Shanghai 2021tszk01Postdoctoral Research Project of Putuo Hospital affiliated to Shanghai University of Traditional Chinese Medicine 2023-BSH-01Shanghai University of Traditional Chinese Medicine Science and Technology Development Project 23KFL084the National Natural Science Foundation of China 81973700
6 · The paper itself

Abstract

Photothermal therapy (PTT) is a promising non-invasive treatment that has shown great potential in eliminating tumors. It not only induces apoptosis of cancer cells but also triggers immunogenic cell death (ICD) which could activate the immune system against cancer. However, the immunosuppressive tumor microenvironment (TIME) poses a challenge to triggering strong immune responses with a single treatment, thus limiting the therapeutic effect of cancer immunotherapy. In this study, dual-targeted nano delivery system (GOx@FeNPs) combined with αPD-L1 immune checkpoint blocker could inhibit colorectal cancer (CRC) progression by mediating PTT, ferroptosis and anti-tumor immune response. Briefly, specific tumor delivery was achieved by the cyclic arginine glycyl aspartate (cRGD) peptide and anisamide (AA)  in GOx@FeNPs which not only had a good photothermal effect to realize PTT and induce ICD, but also could deplete glutathione (GSH) and catalyze the production of reactive oxygen species (ROS) from endogenous H

Indexed as

Colorectal NeoplasmsFerroptosisPhotothermal TherapyAnimalsCell Line, TumorFemaleHumansImmune Checkpoint InhibitorsImmunotherapyMagnetic Iron Oxide NanoparticlesMagnetite NanoparticlesMiceMice, Inbred BALB CReactive Oxygen SpeciesTumor MicroenvironmentImmune Checkpoint InhibitorsMagnetite NanoparticlesReactive Oxygen SpeciesCRCFerroptosisICDImmunotherapyPhotothermal therapy

Identifiers

PMID39415226
PMCPMC11484360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.