Evidence map›Paper›PMID 39415182›Full record

ArticleTrials2024

The effectiveness and cost-effectiveness of attachment-based family therapy for young adults with high suicidal ideation: protocol of a randomized controlled trial.

Claudi Bockting, Guy Bosmans, Nele Bergers, Luana Gavan, Mickaël Hiligsmann, Derek de Beurs, Geert Molenberghs, Ben Wijnen, Joran Lokkerbol, Nadia van der Spek

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05965622 (Targeting Suicidality in Young Adults), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05965622 narecruitingnot on this map

Targeting Suicidality in Young Adults: a Randomized, Controlled Pragmatic, Multicentre Trial Evaluating the (Cost)-Effectiveness of Attachment Based Family Therapy Compared to Treatment as Usual

TypeinterventionalSponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2023 to 2026Enrolled138ConditionsSuicidal IdeationArmsAttachment Based Family Therapy (ABFT) + Treatment As Usual (TAU), Treatment As Usual (TAU)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Claudi BocktingDepartment of Psychiatry, Amsterdam University Medical Centre, Location AMC, Amsterdam, North Holland, 1105 AZ, The Netherlands. c.l.bockting@amsterdamumc.nl.
Guy BosmansKU Leuven, Louvain, Flanders, Belgium.
Nele BergersDepartment of Psychiatry, Amsterdam University Medical Centre, Location AMC, Amsterdam, North Holland, 1105 AZ, The Netherlands.
Luana GavanDepartment of Psychiatry, Amsterdam University Medical Centre, Location AMC, Amsterdam, North Holland, 1105 AZ, The Netherlands.
Mickaël HiligsmannFaculty of Health Medicine and Life Sciences, Maastricht University, Maastricht, Limburg, The Netherlands.
Derek de BeursUniversity of Amsterdam, Amsterdam, Noord-Holland, The Netherlands.
Geert MolenberghsHasselt University, Hasselt, Limburg, Belgium.
Ben WijnenCenter of Economic Evaluation, Trimbos-Instituut, Utrecht, The Netherlands.
Joran LokkerbolMental Health and Addiction, Trimbos-Instituut, Utrecht, The Netherlands.
Nadia van der SpekDepartment of Psychiatry, Amsterdam University Medical Centre, Location AMC, Amsterdam, North Holland, 1105 AZ, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundYoung adult suicidality is worldwide a prevalent mental health problem and the number one cause of death, with devastating consequences for individuals and their families, and substantial economic costs. However, psychological and pharmacological treatments currently recommended in guidelines for treatment of high-risk youth for fatal suicide have limited effect. In line with the World Health Organization's (WHO) recommendation to involve the family in treatment of these youth, attachment-based family therapy (ABFT) was developed, a 16-week attachment and emotion-focused treatment, implemented in mental health care settings across various European countries in the past years, and becoming increasingly popular among therapists. However, the (cost-)effectiveness of ABFT has not been studied in emerging adults. In the proposed pragmatic randomized controlled trial (RCT), we aim to evaluate the effectiveness and cost-effectiveness of ABFT compared to treatment as usual (TAU) on suicidality, as delivered in daily practice.

methodsThis pragmatic multicenter study in the Netherlands and Belgium includes 13 participating sites. Participants are suicidal young adults (≥ 31 SIQ-JR score) between 16 and 30 years old who seek mental health treatment (n = 142) and their caregivers. The primary outcome is suicidality (SIQ-JR), with assessments at baseline, post-intervention (5 months after baseline), 3, 6, and 12 months after intervention. We predict that, compared to TAU, ABFT will lead to a stronger reduction in suicidality and will be more cost-effective, over the course of all time points. We also expect stronger decreases in depressive symptoms, given that suicidality is very common in individuals with depressive disorder, as well as more improvement in family functioning, autonomy, entrapment, and young adult attachment, in the ABFT condition. DISCUSSION: This study can contribute to improving the care for suicidal youngsters with high mortality risk. Treatment of suicidal emerging adults is understudied. The results will inform clinical guidelines and policy makers and improve treatment of suicidal emerging adults.

trial registrationThis trial is registered on ClinicalTrials.gov (NCT05965622, first posted on July 28, 2023).

Indexed as

Cost-Benefit AnalysisFamily TherapyMulticenter Studies as TopicPragmatic Clinical Trials as TopicSuicidal IdeationAdolescentAdultBelgiumFemaleHealth Care CostsHumansMaleNetherlandsObject AttachmentRandomized Controlled Trials as TopicSuicide PreventionAttachment-based family therapyCost-effectivenessPsychotherapyRandomized controlled trialSuicidal ideationSuicidalitySuicide preventionYoung adult

Identifiers

PMID39415182
PMCPMC11484370

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.