Trial reportBMC oral health2024
Full pulpotomy versus root canal therapy in mature teeth with irreversible pulpitis: a randomized controlled trial.
Trial report in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07375576 (Evaluation of the Outcomes of Total Pulpotomy, Radicular Pulpotomy, and Root Canal Treatment in Teeth With Extremely Deep Caries and Symptomatic Irreversible Pulpitis), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Outcomes of Total Pulpotomy, Radicular Pulpotomy, and Root Canal Treatment in Teeth With Extremely Deep Caries and Symptomatic Irreversible Pulpitis
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Analgesic Efficacy of Low-Level Laser Therapy for Postoperative Endodontic Pain: A Systematic Review and Meta-Analysis.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Pooled it
- Twenty-four-month outcomes of full pulpotomy in permanent molars with symptomatic irreversible pulpitis: a randomized controlled trial of adjunctive cryotherapy.Clinical oral investigations · 2026Trial
- Histological evaluation of vital full pulpotomy techniques in permanent mature teeth with symptomatic irreversible pulpitis using three calcium silicate cements: a randomized controlled trial.BMC oral health · 2025Trial
- Review
- Comparison Between Human Amniotic Membrane and Biodentine as A Pulp Capping Agent-An In Vitro Tooth Culture Study.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Evaluation of Time-Dependent Chemical Alterations in Sodium Hypochlorite Solution Kept on the Unit Tray During an Average Root Canal Treatment Period.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Determinants of Definitive Full Pulpotomy Adoption in Symptomatic Irreversible Pulpitis: A Multivariable Analysis of Dental Trainee Decision-Making.Healthcare (Basel, Switzerland) · 2026Article
- Postoperative Pain and Matrix Metalloproteinase-9 Pulpal Blood Level in Symptomatic Pulpitis of Mature Molars Treated with Biodentine and Portland Cement Full Pulpotomy: A Randomized Clinical Trial.Journal of clinical and experimental dentistry · 2026Review
- Clinical Challenges and Therapeutic Approaches in Managing Deep Carious Lesions Close to the Pulp in Permanent Teeth: A Narrative Review.International journal of dentistry · 2026Review
- Pulp sensibility assessment following permanent tooth pulpotomy: a scoping review of clinical studies.Frontiers in dental medicine · 2026Review
- Decision-ready evidence for vital pulp therapy: a network meta-analysis of bioactive materials in mature permanent teeth.Frontiers in dental medicine · 2026Review
- Objectively Diagnosing Pulpitis: Opportunities and Methodological Challenges in the Development of Point-of-Care Assays.International journal of molecular sciences · 2025Review
- Symptom correlation and spatial distribution of inflammatory mediators in pulpitis-A preliminary study.International endodontic journal · 2025Article
- Post-operative pain and success rate after pulpotomy with symptomatic irreversible pulpitis: A review.Bioinformation · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundVital pulp therapy (VPT) is recommended as an alternative treatment to root canal therapy (RCT) for management of teeth with carious pulp exposure. This randomized clinical trial aimed to compare the outcomes and postoperative pain, and to evaluate the time and cost after full pulpotomy (FP) and RCT in mature molar teeth with irreversible pulpitis (IP).
methodsA total of 160 mature molar teeth with IP were randomly divided into two treatment groups. The FP group (test group) was treated with FP using iRoot BP Plus by an endodontist, the RCT group (control group) was treated with RCT using iRoot SP as sealer by the same endodontist. Pain was recorded preoperatively and daily until day 7 postoperatively. The treatment time and cost were recorded. Clinical and radiographic assessments were collected, and pulp sensibility tests were done by electric pulp test (EPT) at 3-, 6-, 12- month postoperatively. Data were analyzed through chi-square test, Mann-Whitney U test, Fisher exact and independent t test.
resultsFP and RCT had comparable success rates (Clinical, 97.3% vs. 98.6%; radiographic, 93.3% vs. 94.6%) (P > 0.05). Pain levels decreased over time from day 1 to day 7 postoperative in both groups, and the FP group had larger reductions in pain intensity than RCT at day 1 (P < 0.05). In the FP group, there were 5, 3 and 3 unresponsive teeth with EPT at 3-, 6- and 12- month follow-ups, respectively. The treatment time and cost in the FP group were significantly lower than in the RCT group (P < 0.05).
conclusionsFP could be an appropriate alternative treatment for management of mature teeth with IP in short follow-up.
trial registrationThe trial was registered in Chinese Clinical Trial Registry (ChiCTR2200063380 at 05/09/2022).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.