Evidence map›Paper›PMID 39415115›Full record

ArticleBMC genomics2024

Genomic epidemiology of ceftriaxone-resistant non-typhoidal Salmonella enterica strain in China.

Danni Bao, Lei Chen, Weiwei Shen, Xiaohong Xu, Lifei Zhu, Yizhang Wang, Yanhong Wu, Xianhong He, Fengjiao Zhu, Hongzhang Li

Abstract read
In one paragraph

Article in BMC genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Microbiology spectrum · 2026
    Article
  5. Article
  6. Stool carriage of CTX-M/CMY-producingFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Danni Bao *Department of Clinical Laboratory, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, 317100, Zhejiang, China.
Lei Chen *Department of Clinical Laboratory, The Third Affiliated Hospital of Wenzhou Medical University, Zhejiang, China.
Weiwei ShenTaizhou Center for Disease Control and Prevention, Taizhou, China.
Xiaohong XuDepartment of Clinical Laboratory, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, 317100, Zhejiang, China.
Lifei ZhuDepartment of Clinical Laboratory, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, 317100, Zhejiang, China.
Yizhang WangDepartment of Clinical Laboratory, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, 317100, Zhejiang, China.
Yanhong WuDepartment of Clinical Laboratory, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, 317100, Zhejiang, China.
Xianhong HeDepartment of Clinical Laboratory, The Third People's Hospital of Xiaoshan, Hangzhou, China.
Fengjiao ZhuDepartment of Clinical Laboratory, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, 317100, Zhejiang, China. zhufengjiao@zjsmyy.com.
Hongzhang LiDepartment of Gastroenterology, Sanmen Bay Branch of The First Affiliated Hospital, Sanmen People's Hospital, Zhejiang University School of Medicine, Taizhou, Zhejiang, 317100, China. lihongzhang@zjsmyy.com.

Funding

Zhejiang Provincial Medical and Health Science and Technology Plan 2023KY414Zhejiang Provincial Medical and Health Science and Technology Plan 2024KY1441Zhejiang Provincial Natural Science Foundation of China LQ24H200003
6 · The paper itself

Abstract

Non-typhoidal Salmonella (NTS) is one of the top causes of diarrhea worldwide. Ceftriaxone is commonly recommended as the initial treatment option for Salmonella infections due to its antibacterial effectiveness. The objective of this study was to investigate the molecular epidemiological characteristics of NTS and to compare the phenotypic and genotypic profiles of antimicrobial resistance in multidrug-resistant Salmonella strains by sequencing 329 NTS strains collected from a county-level hospital between 2018 and 2021. Multi-locus sequence typing (MLST), antimicrobial resistance genes and plasmid types were identified by BacWGSTdb 2.0 webserver. Phylogenetic analysis of all NTS strains was carried out using Snippy and Gubbins software. The transferability of ceftriaxone resistant plasmids was confirmed through plasmid conjugation assays, and verified by S1-PFGE-Southern blot assays. The predominant serotypes among all NTS strains were Typhimurium (161/329), Enteritidis (49/329) and London (45/329). The most common sequence type observed was ST34 (86/329), followed by ST19 (72/329) and ST11 (47/329). The antimicrobial resistance of Salmonella to a wide range of antimicrobials showed an overall increase. Out of these 37 (11.24%) ceftriaxone-resistant strains, with the majority of them (33/37) being bla

Indexed as

Anti-Bacterial AgentsCeftriaxonePhylogenyPlasmidsSalmonella entericaSalmonella InfectionsChinaDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsMolecular EpidemiologyMultilocus Sequence TypingAnti-Bacterial AgentsCeftriaxoneAntimicrobial resistanceCeftriaxoneHorizontal gene transferPlasmidSalmonella entericaWhole-genome sequencing

Identifiers

PMID39415115
PMCPMC11484373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.