Evidence map›Paper›PMID 39414999›Full record

ArticleNPJ digital medicine2024

A randomized clinical trial testing digital mindset intervention for knee osteoarthritis pain and activity improvement.

Melissa A Boswell, Kris M Evans, Disha Ghandwani, Trevor Hastie, Sean R Zion, Paula L Moya, Nicholas J Giori, Jennifer L Hicks, Alia J Crum, Scott L Delp

Registry-linked trialAbstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05698368 (A Digital Mindset Intervention to Improve Pain and Exercise Participation in Individuals With Knee Osteoarthritis), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05698368 nacompletednot on this map

A Digital Mindset Intervention to Improve Pain and Exercise Participation in Individuals With Knee Osteoarthritis: A Randomized, Parallel-group Study

TypeinterventionalSponsorStanford UniversityRan2023 to 2023Enrolled458ConditionsKnee OsteoarthritisArmsMindset intervention, Active comparator
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melissa A BoswellJoe Gibbs Human Performance Institute, Huntersville, NC, 28078, USA. mboswell@jghpi.com.ORCID http://orcid.org/0000-0003-2014-9809
Kris M EvansDepartment of Psychology, Stanford University, Stanford, CA, 94305, USA.
Disha GhandwaniDepartment of Statistics, Stanford University, Stanford, CA, 94305, USA.
Trevor HastieDepartment of Statistics, Stanford University, Stanford, CA, 94305, USA.
Sean R ZionDepartment of Psychology, Stanford University, Stanford, CA, 94305, USA.
Paula L MoyaDepartment of English, Stanford University, Stanford, CA, 94305, USA.
Nicholas J GioriDepartment of Orthopedic Surgery, Stanford University, Stanford, CA, 94305, USA.
Jennifer L HicksDepartment of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
Alia J Crum *Department of Psychology, Stanford University, Stanford, CA, 94305, USA.
Scott L Delp *Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.

Funding

TR&D Project 3: OpenSim for PredictionP41EB027060 · NIBIB · STANFORD UNIVERSITY · PI SCOTT L DELP · 2020 to 2026
$9.7M
FOXO3 Genotype, InflammAging, Cardiovascular Disease, and Dementia. Kuakini Hawaii Lifespan Study III. Administrative Supplement.R01AG027060 · NIA · KUAKINI MEDICAL CENTER · PI Gregory J. Tranah, BRADLEY JOHN WILLCOX · 2005 to 2026
$8.1M
Technology DevelopmentP2CHD101913 · NICHD · STANFORD UNIVERSITY · PI DELP, SCOTT L · 2020 to 2024
$4.1M
NIBIB NIH HHS P41 EB027060NICHD NIH HHS P2C HD101913U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) P41EB027060U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) P2CHD101913
6 · The paper itself

Abstract

This randomized clinical trial evaluated the effectiveness of short, digital interventions in improving physical activity and pain for individuals with knee osteoarthritis. We compared a digital mindset intervention, focusing on adaptive mindsets (e.g., osteoarthritis is manageable), to a digital education intervention and a no-intervention group. 408 participants with knee osteoarthritis completed the study online in the US. The mindset intervention significantly improved mindsets compared to both other groups (P < 0.001) and increased physical activity levels more than the no-intervention group (mean = 28.6 points, P = 0.001), but pain reduction was not significant. The mindset group also showed significantly greater improvements in the perceived need for surgery, self-imposed physical limitations, fear of movement, and self-efficacy than the no-intervention and education groups. This trial demonstrates the effectiveness of brief digital interventions in educating about osteoarthritis and further highlights the additional benefits of improving mindsets to transform patients' approach to disease management. The study was prospectively registered (ClinicalTrials.gov: NCT05698368, 2023-01-26).

Identifiers

PMID39414999
PMCPMC11484881

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.