Evidence map›Paper›PMID 39414974›Full record

ArticleNature neuroscience2025

Rastermap: a discovery method for neural population recordings.

Carsen Stringer, Lin Zhong, Atika Syeda, Fengtong Du, Maria Kesa, Marius Pachitariu

Abstract read
In one paragraph

Article in Nature neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Article
  3. Heterogeneous Medial Prefrontal Cortex Ensembles Exhibit Reproducible Internal Temporal Dynamics during Choice Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  4. Article
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  8. Article
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  12. CA1 Engram Cell Dynamics Before and After Learning.bioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carsen StringerHoward Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA. stringerc@janelia.hhmi.org.ORCID http://orcid.org/0000-0002-9229-4100
Lin ZhongHoward Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.ORCID http://orcid.org/0000-0002-9740-628X
Atika SyedaHoward Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.ORCID http://orcid.org/0000-0002-3097-4071
Fengtong DuHoward Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.
Maria KesaHoward Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA.
Marius PachitariuHoward Hughes Medical Institute Janelia Research Campus, Ashburn, VA, USA. pachitarium@janelia.hhmi.org.ORCID http://orcid.org/0000-0001-7106-814X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurophysiology has long progressed through exploratory experiments and chance discoveries. Anecdotes abound of researchers listening to spikes in real time and noticing patterns of activity related to ongoing stimuli or behaviors. With the advent of large-scale recordings, such close observation of data has become difficult. To find patterns in large-scale neural data, we developed 'Rastermap', a visualization method that displays neurons as a raster plot after sorting them along a one-dimensional axis based on their activity patterns. We benchmarked Rastermap on realistic simulations and then used it to explore recordings of tens of thousands of neurons from mouse cortex during spontaneous, stimulus-evoked and task-evoked epochs. We also applied Rastermap to whole-brain zebrafish recordings; to wide-field imaging data; to electrophysiological recordings in rat hippocampus, monkey frontal cortex and various cortical and subcortical regions in mice; and to artificial neural networks. Finally, we illustrate high-dimensional scenarios where Rastermap and similar algorithms cannot be used effectively.

Indexed as

NeuronsZebrafishAction PotentialsAlgorithmsAnimalsBrainComputer SimulationMiceModels, NeurologicalNeural Networks, ComputerRats

Identifiers

PMID39414974
PMCPMC11706777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.