Evidence map›Paper›PMID 39414939›Full record

ArticleEye (London, England)2025

Living histopathology - interrogation of ocular tissues by light: a celebration of the slit-lamp and a repertoire of clinical techniques.

Paul A R Meyer

Abstract readHistorical ArticleVideo-Audio Media
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Paul A R MeyerVisiting Fellow, Cambridge University Department of Engineering; Hon Senior Visiting Fellow, Cambridge University Department of Medicine; Retired Consultant Medical Ophthalmologist, Addenbrooke's Hospital, Cambridge, UK. parm2@cam.ac.uk.ORCID http://orcid.org/0000-0001-7151-4795

Funding

Wellcome Trust
6 · The paper itself

Abstract

The evolution of the slit-lamp microscope has enabled ophthalmologists to examine the transparent tissues of the eye with histological detail. This paper considers the history and optics of the slit-lamp. Optical sectioning and retro-illumination are discussed; particularly, effective placement of the reflected light beam. A variety of less conventional slit-lamp examination techniques is described. These include remote dark-field retro-illumination, examination through refractive surfaces (particularly, meniscus retro-illumination to demonstrate tear cells and non-contact corneal endothelial specular microscopy), location of vitreous abnormalities by parallax, expanding radial cords of vitreous cells in lymphoma, mirror examination of the superior fornix and corneal epithelial folds in ocular hypotension. It concludes with brief discussions about haemoglobin video imaging, semi-quantification of aqueous outflow volume by aqueous column cross-section area, and autofocus for video-microscopy.

Indexed as

Diagnostic Techniques, OphthalmologicalEyeEye DiseasesSlit LampSlit Lamp MicroscopyHistory, 20th CenturyHumans

Identifiers

PMID39414939
PMCPMC11885458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.