Evidence map›Paper›PMID 39414911›Full record

ArticleJournal of public health policy2024

Screening participants with inflammatory bowel disease or high colorectal cancer risk in Denmark: a cohort study.

Signe Bülow Therkildsen, Pernille Thordal Larsen, Sisse Helle Njor

Abstract read
In one paragraph

Article in Journal of public health policy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Signe Bülow TherkildsenDepartment of Public Health Programmes, University Research Clinic for Cancer Screening, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark.
Pernille Thordal LarsenDepartment of Public Health Programmes, University Research Clinic for Cancer Screening, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark.
Sisse Helle NjorDepartment of Public Health Programmes, University Research Clinic for Cancer Screening, Randers Regional Hospital, Skovlyvej 15, 8930, Randers NØ, Denmark. sisse.helle.njor@rsyd.dk.ORCID http://orcid.org/0000-0003-0429-4176

Funding

Aage og Johanne Louis-Hansens Fond 20-2B-6191Kræftens Bekæmpelse R269-A15801
6 · The paper itself

Abstract

Individuals with inflammatory bowel disease (IBC) and high-risk individuals are advised to discuss participation with their doctor and not to participate in colorectal cancer (CRC) screening. Yet a substantial proportion still participate in the Danish faecal immunochemical test (FIT) screening and have a higher positive FIT rate than the average-risk population. We estimated the risk of false-positive screening among individuals with inflammatory bowel disease and high-risk individuals to improve recommendations regarding screening participation. We included 71,871 FIT-positive participants (2014-2017) who had a subsequent colonoscopy within 3 months. Screening outcome within 180 days was established by using registers. We determined that 26,591 of the included participants had a false-positive screening. Participants with IBC or high CRC risk had a significantly higher risk of getting a false-positive screening than the average risk population, resulting in too many screening-related colonoscopies being performed among these individuals, indicating a need to update the screening protocols.

Indexed as

ColonoscopyColorectal NeoplasmsEarly Detection of CancerInflammatory Bowel DiseasesAdultAgedCohort StudiesDenmarkFalse Positive ReactionsFemaleHumansMaleMass ScreeningMiddle AgedOccult BloodRisk FactorsColorectal cancer screeningFalse-positiveFIT screeningHigh-risk individualsInflammatory bowel diseaseRecommendations

Identifiers

PMID39414911
PMCPMC11609084

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.