ArticleNature communications2024
Inorganic nitrogen inhibits symbiotic nitrogen fixation through blocking NRAMP2-mediated iron delivery in soybean nodules.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed.
- Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Optimizing Irrigation and Nitrogen Inputs for Balancing Greenhouse Gas Mitigation, Productivity, and Profitability in an Intercropping System of Wolfberry and Alfalfa.Plants (Basel, Switzerland) · 2026Article
- Interactive effects of field pea genotypes and Rhizobium Leguminosarum strains on nodulation, yield, and nitrogen fixation in Sinana district, Ethiopia.BMC plant biology · 2026Article
- OsbHLH064, an IVb bHLH Transcription Factor, Regulates Iron Homeostasis and Enhances Grain Fe Accumulation in Rice.Plant biotechnology journal · 2026Article
- Molecular Evolution and Mechanisms of Plants NRAMP Transporters in Response to Heavy Metal Stress.Plants (Basel, Switzerland) · 2026Review
- Assessment of Disease-Suppressive and Plant Growth-Promoting Capabilities ofJournal of fungi (Basel, Switzerland) · 2026Article
- Systemic Effects of Nitrate, Asparagine, and Glutamine on Nodulation and Biological Nitrogen Fixation in Soybean.Plants (Basel, Switzerland) · 2026Article
- Identification of symbiotic nitrogen fixation-modulating factors in alfalfa and mechanism elucidation of MsHHO3.The Plant journal : for cell and molecular biology · 2026Article
- Iron need attention: a review on the role of iron in plants.Frontiers in plant science · 2026Review
- Nutrient storage and release in uninfected cells of soybean nodules support symbiotic nitrogen fixation in infected cells.aBIOTECH · 2025Article
- Optimizing mung bean productivity and root morphology with biofertilizers for sustainable farming.Scientific reports · 2025Article
- Maintaining sulfur supply to the symbiosome delays nodule senescence in soybean.Nature communications · 2025Article
- Iron-Integrated Nitrogen-Rich Nanocarriers Boost Symbiotic Nitrogen Fixation and Growth in Soybean (Nanomaterials (Basel, Switzerland) · 2025Article
- Deciphering crop-specific rhizobacteriome assembly in cotton, sorghum, and soybean under hot semi-arid field conditions in Texas.Environmental microbiome · 2025Article
- Genome-Wide Identification and Evolutionary Analysis of the GATA Transcription Factor Family in Nitrogen-Fixing Legumes.Plants (Basel, Switzerland) · 2025Article
- Micronutrients: Minor yet crucial for symbiotic nitrogen fixation.Plant communications · 2025Article
- Barriers and carriers for transition metal homeostasis in plants.Plant communications · 2025Review
- Earthworms With Low Dose n-MoSPhysiologia plantarumArticle
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Authors and funding
16 authors.
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Abstract
Symbiotic nitrogen fixation (SNF) in legume-rhizobia serves as a sustainable source of nitrogen (N) in agriculture. However, the addition of inorganic N fertilizers significantly inhibits SNF, and the underlying mechanisms remain not-well understood. Here, we report that inorganic N disrupts iron (Fe) homeostasis in soybean nodules, leading to a decrease in SNF efficiency. This disruption is attributed to the inhibition of the Fe transporter genes Natural Resistance-Associated Macrophage Protein 2a and 2b (GmNRAMP2a&2b) by inorganic N. GmNRAMP2a&2b are predominantly localized at the tonoplast of uninfected nodule tissues, affecting Fe transfer to infected cells and consequently, modulating SNF efficiency. In addition, we identified a pair of N-signal regulators, nitrogen-regulated GARP-type transcription factors 1a and 1b (GmNIGT1a&1b), that negatively regulate the expression of GmNRAMP2a&2b, which establishes a link between N signaling and Fe homeostasis in nodules. Our findings reveal a plausible mechanism by which soybean adjusts SNF efficiency through Fe allocation in response to fluctuating inorganic N conditions, offering valuable insights for optimizing N and Fe management in legume-based agricultural systems.
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