Evidence map›Paper›PMID 39414774›Full record

ArticleNature communications2024

All-optical reporting of inhibitory receptor driving force in the nervous system.

Joshua S Selfe, Teresa J S Steyn, Eran F Shorer, Richard J Burman, Kira M Düsterwald, Ariel Z Kraitzick, Ahmed S Abdelfattah, Eric R Schreiter, Sarah E Newey, Colin J Akerman and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joshua S SelfeDivision of Cell Biology, Department of Human Biology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0001-6605-0690
Teresa J S SteynDivision of Cell Biology, Department of Human Biology, University of Cape Town, Cape Town, South Africa.
Eran F ShorerDivision of Cell Biology, Department of Human Biology, University of Cape Town, Cape Town, South Africa.
Richard J BurmanDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.
Kira M DüsterwaldDivision of Cell Biology, Department of Human Biology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-3217-5326
Ariel Z KraitzickDivision of Cell Biology, Department of Human Biology, University of Cape Town, Cape Town, South Africa.ORCID 0000-0002-0466-8636
Ahmed S AbdelfattahDepartment of Neuroscience, Brown University, Providence, Rhode Island, United States of America.ORCID 0000-0001-8131-1772
Eric R SchreiterJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, United States of America.ORCID 0000-0002-2864-7469
Sarah E NeweyDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8941-4039
Colin J AkermanDepartment of Pharmacology, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-6844-4984
Joseph V RaimondoDivision of Cell Biology, Department of Human Biology, University of Cape Town, Cape Town, South Africa. joseph.raimondo@uct.ac.za.ORCID 0000-0002-8266-3128

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) 617670RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/S007938/1Royal Society FLR\R1\190829Wellcome TrustWellcome Trust (Wellcome) 214042/Z/18/ZWellcome Trust (Wellcome) 222968/Z/21/Z
6 · The paper itself

Abstract

Ionic driving forces provide the net electromotive force for ion movement across receptors, channels, and transporters, and are a fundamental property of all cells. In the nervous system, fast synaptic inhibition is mediated by chloride permeable GABA

Indexed as

NeuronsReceptors, GABA-ASynaptic TransmissionAnimalsAstrocytesChloridesHumansMaleMiceReceptors, GlycineChloridesReceptors, GABA-AReceptors, Glycine

Identifiers

PMID39414774
PMCPMC11484818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.